浅析高原红细胞增多与血尿酸的关系  

Relation between High Altitude Polycythenia and Serum Uric Acid

作　　者：刘成海[1] 吕国志[1] 吴彦民[1] 杨聪[1] 杨五洪[1] 文朝远[1] 

机构地区：[1]解放军第115医院内科,西藏林芝860000

出　　处：《西南军医》2017年第5期407-408,共2页Journal of Military Surgeon in Southwest China

摘　　要：目的观察高原红细胞增多对血尿酸(UA)水平的影响,为高原地区研究高尿酸血症的机制奠定基础。方法选择刚进藏新兵99名,将其分为0月(对照组)和1、2、6、12个月(观察组),检测各组血红蛋白(HGB)及血尿酸水平并作比较分析。结果各观察组血红蛋白水平明显高于正常对照组(P<0.05),各观察组血尿酸水平也明显高于正常对照组(P<0.05),且血尿酸水平变化与高原红细胞增多有明显的相关性。结论高原红细胞增多是引起高尿酸血症的因素之一。Objective To observe the effect of high altitude polycythenia on the level of serum uric acid （UA） so as to lay a basis for the mechanism research of hyperuricemia at high altitude. Methods 99 new recruits newly arrived in Tibet were divided into 2 groups ： control group （just arrived in Tibet） and observation group （ including 4 sub-groups ： 1-month sub-group, 2-month sub-group, 6-month sub-group and 12-month sub-group）; the levels of hemoglobin （HGB） and UA of the cases in each group were observed and a comparative analysis was made. Results The levels of HGB and UA in observation group was much higher than those in control group （P 〈 0.05 ） ; there existed an obvious correlation between the level changes of UA and high altitude polycythenia. Conclusions High altitude polycythenia is one of the factors leading to the occurrence of hyperuricemia.

关 键 词：高原红细胞增多 高原地区 尿酸 

分 类 号：R555.1[医药卫生—血液循环系统疾病]