真武汤治疗脓毒症急性肾损害少尿期的疗效研究  

Effects of Zhenwu decoction on acute renal damage of sepsis with oliguria

作　　者：樊艺[1] 李莉[1] 周竞争 霍锐[1] 

机构地区：[1]重庆市中医院重症医学科,重庆400020

出　　处：《临床医药文献电子杂志》2017年第38期7338-7339,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的研究真武汤对脓毒症患者急性肾损害少尿期的临床疗效。方法将我院2016年3月~2017年3月脓毒症患者中出现急性肾损害并且辨证为阳虚水泛证的28例患者作为研究对象,随机分为观察组和对照组,对照组进行西医常规治疗;观察组在对照组的基础上加以真武汤治疗。分别监测两组患者治疗前后的APACHEⅡ、SOAF评分及每日尿量,血乳酸、血肌酐及血清钾离子水平等指标。结果观察组总有效率70.4%明显优于对照组总有效率52.3%。治疗后两组中一部分患者尿量增多,不需要进步一行CRRT治疗(P<0.05)。结论真武汤对于阳虚水泛型脓毒症急性肾损害少尿期患者的肾功能有更进一步保护作用。Objective To explore the clinical effects of Zhenwu decoction on sepsis acute kidney injury oliguria. Methods Our hospital from January 2016 to March 2017 sepsis patients with acute kidney damage,and differe.ntiation of syndrome of water over-flowing due to YANG-insufficiency into the group,The patients were randomly divided into observation group and control group.The control group received routine western medicine treatment, The observation group to conventional therapy in western medicine group on Zhenwu decoction.Two groups of patients were monitored for 24 hours urine volume,renal function,creatinine clearance rate and other indicators. Results The total effective rate was 70.4% in the treatment group and 52.3% in the control group.After treatment,Two groups of patients with increased urine volume,do not need to progress a row of CRRT treatment,Chinese medicine group is significantly better than western medicine group（P〈0.05）. Conclusion Zhenwu decoction for syndrome of water over-flowing due to YANG-insufficiency sepsis acute kidney injury and renal function in patients with less urine have a better protective effect.

关 键 词：脓毒症 急性肾损害 真武汤 阳虚水泛症 

分 类 号：R459.7[医药卫生—急诊医学]