2-位官能团化合成2-取代苯并噻唑的研究进展  

Progress in 2-Position Functionalized Synthesis of 2-Substitutedbenzothiazoles

作　　者：戴小强 朱亚波[1] 汪洲洋 翁建全[1] 

机构地区：[1]浙江工业大学化学工程学院,杭州310014

出　　处：《有机化学》2017年第8期1924-1938,共15页Chinese Journal of Organic Chemistry

基　　金：国家自然科学基金(No.30900959);浙江省自然科学基金(No.LY17C140003)资助项目~~

摘　　要：2-取代苯并噻唑类衍生物在化工、医药、农业等领域具有广泛的应用价值.2-位官能团化是合成2-取代苯并噻唑化合物的一种便捷、有效的合成方法.综述了苯并噻唑2-位的烷基化、酰基化、芳基化、胺基化以及磷酸化等产物的合成方法并进行了归类和分析,同时对其发展进行了展望.2-Substitutedbenzothiazole derivatives were widely used in chemical, pharmaceutical and agricultural fields.2-Position functionalized method was a convenient and effective way to synthesize 2-substitutedbenzothiazoles. In this paper, the methods for the synthesis of 2-substitutedbenzothiazoles by the alkylation, acylation, arylation, amination and phosphorylation reactions at the 2-position are reviewed, and their future outlook is also discussed.

关 键 词：苯并噻唑 2-位官能团化 烷基化 酰基化 芳基化 胺基化 磷酸化 

分 类 号：O626.25[理学—有机化学]