绿草定酯的合成工艺研究  

Research on the Synthesis of Triclopyr Ester

作　　者：赵志雄[1] 何灏彦[1] 

机构地区：[1]湖南化工职业技术学院化工系,湖南株洲412004

出　　处：《山东化工》2017年第17期6-8,共3页Shandong Chemical Industry

摘　　要：绿草定是广泛使用的除草剂种类之一。本文设计了以氯乙酸甲酯和3,5,6-三氯-2-吡啶酚钠为原料、N,N-二甲基甲酰胺作溶剂生产绿草定中间体绿草定酯的工艺路线,研究了原料配比、溶剂配比、反应温度、反应时间4个因素对反应过程的影响。实验结果表明,原料氯乙酸甲酯和3,5,6-三氯-2-吡啶酚钠的物质的量配比2.00,溶剂N,N-二甲基甲酰胺与3,5,6-三氯-2-吡啶酚钠的质量配比2.25,反应温度65℃,反应时间6 h为合成绿草定酯的最佳工艺条件,绿草定酯的收率可达96.85%。Triclopyr is one of the most widely used herbicides. Refering to currently existing methods of synthesizing triclopyr,we innovatively designed the synthesis route of intermediate triclopyr by utilizing Sodium Salt of Trichloro Pyridinol,Methyl Chloroacetate as raw materials and DMF as reaction solvent. In addition,the influence of molar ratio of reactants,reaction solvent,temperature and time on conversion of reaction were elaborately investigated,which came to the conclusion that molar ratio（ n（ MC） ∶ n（ Na TCP）） of 2. 00,solvent mass ratio of 2. 25,reaction temperature of 65 ℃,reaction time of 6h are optimal reaction conditions with a high yield of 96. 85%.

关 键 词：绿草定中间体 绿草定酯 合成工艺 

分 类 号：TQ457.2[化学工程—农药化工]