母乳强化剂对早产儿心脏功能的影响  

Effects of human milk fortifier on premature infant＇s cardiac function

作　　者：邹积茹[1] 叶立伟[1] 曹立杰[1] 王秀娟[1] 

机构地区：[1]黑龙江省大庆龙南医院儿科,163000

出　　处：《中华现代护理杂志》2017年第18期2365-2367,共3页Chinese Journal of Modern Nursing

基　　金：国家卫生计生委医药卫生科技发展研究中心课题(W2015EAE107)China National Health Development Research Center Project

摘　　要：目的探讨母乳添加剂对早产儿心脏功能的影响。方法2014年1月-2016年12月选择黑龙江省大庆龙南医院儿科60例早产儿为研究对象。采用随机数字表法随机分为试验组（乳汁喂养＋强化剂）30例和对照组（单纯乳汁喂养）30例。监测应用母乳强化剂前、中及停用后试验组早产儿心率的变化及应用母乳强化剂1周后比较试验组与对照组早产儿的心率、心电图（心率、P波时限、QRS波宽度、P-R间期、心律失常发生率）、超声心动图情况（LVEF、RVEF及二、三尖瓣口的E／A比值）及心肌酶学（谷草转氨酶（AST）、乳酸脱氢酶（LDH）、肌酸激酶（cK）、肌酸激酶一同工酶（CK-MB））的变化。结果试验组早产儿应用母乳强化剂时的早产儿心率快于应用前、停用后及对照组的早产儿的心率，差异均有统计学意义护〈0．05），但试验组与对照组早产儿心电图的P波时限、QRS波宽度、P-R间期，超声心动图中的心脏的收缩、舒张功能及心肌酶学差异均无统计学意义（P〉0．05）。结论虽然应用母乳强化剂可以使该类早产儿的心率增快，但对其心电活动、心脏的泵功能及心肌酶无不良影响。Objective To investigate the effects of human milk fortifier on premature infant＇s cardiac function. Methods From January 2014 to December 2016, sixty premature infants of paediatric preterm infants were selected from Daqing Longnan Hospital, Heilongjiang province. The random number table method was divided into 30 cases （milk feeding and strengthening agent） and the control group of 30 cases （pure milk feeding）.The heart rate of premature infant was measured before, during and after using human milk fortifier. After using human mike fortifier for 1 week, heart rate, electrocardiogram （p-wave duration, QRS wave duration, P-R interval, incidence of arrhythmia）, echocardiogram （LVEF, RVEF, E/A ratio of mitral and tricuspid valves） and myocardial enzymes （the quantity of AST, LDH, CK and CK-MB） were compared between experimental group and control group. Results The heart rate of premature infant during using human milk fortifier was significantly faster than those before and after using human milk fortifier and that of children in the control group （P 〈 0.05）. There were no statistically significant differences in electrocardiogram （p-wave duration, QRS wave duration, P-R interval）, the systolic and diastolic function of the heart and myocardial enzymes between the experimental and control groups （P〉0.05）. Conclusions Human milk fortifier can increase the heart rate of premature infant, and has no harmful effect on cardiac electrical activity, pump function and myocardial enzymes.

关 键 词：婴儿 早产 母乳强化剂 心脏功能 

分 类 号：R473.72[医药卫生—护理学]