老年高血压伴主动脉夹层患者临床及病理分析  

Clinical and Pathological Analysis of Elderly Hypertensive Patients with Aortic Dissection

作　　者：吕振云 

机构地区：[1]内蒙古锡林郭勒盟苏尼特右旗人民医院

出　　处：《世界最新医学信息文摘》2017年第24期48-49,共2页World Latest Medicine Information Electronic Version

摘　　要：目的对老年高血压伴主动脉夹层患者的临床表现和病理特征进行分析。方法以2016年1月-2017年1月在本院进行治疗的24例老年高血压伴主动脉夹层患者作为观察组研究对象,以同期24例老年高血压未伴主动脉夹层患者作为对照组研究对象,对两组患者的临床表现和病理特征进行回顾性分析。结果观察组患者的临床表现较对照组患者更复杂,死亡前症状较多,体征异常,以平滑肌肌动蛋白表达能力降低、夹层壁中血管第八因子相关抗原表达性增强以及胶原纤维增生为观察组高血压伴主动脉夹层患者的主要病理特征。结论积极控制老年高血压患者的血压水平可有效预防主动脉夹层。Objective To analyze the clinical manifestations and pathological features of elderly patients with hypertension complicated with aortic dissection. Methods 24 cases of elderly hypertensive patients with aortic dissection treated in our hospital from January 2016 to January 2017 were taken as the object of the observation group, 24 cases of hameochronous elderly hypertensive patients without aortic dissection were taken as the object of the control group. The clinical manifestations and pathological features of patients in the two groups were analyzed retrospectively. Results The clinical manifestations of the patients in the observation group were more complex than those in the control group, and they have more signs ofpre death and abnormal signs. The main pathological features of patients with hypertension and aortic dissection in the observation group were decline of expression of smooth muscle actin, enhancement of the expression of eighth factor related antigen in the blood vessels of the sandwich wall and collagen fiber hyperplasia. Conclusion Active control of blood pressure in elderly hypertensive patients can effectively prevent aortic dissection.

关 键 词：老年高血压 主动脉夹层 临床表现 病理特点 

分 类 号：R544.1[医药卫生—心血管疾病] R543.1[医药卫生—内科学]