直方图分析磁敏感信号强度鉴别乳头状与嫌色细胞肾癌的价值  

Value of histogram analysis of susceptible signal intensity in differentiating papillary from chromophobe renal cell carcinoma

作　　者：陈杰[1] 潘靓[1] 孙军[1] 张京刚[1] 邢伟[1] 

机构地区：[1]江苏省常州市第一人民医院影像科,213003

出　　处：《中华放射学杂志》2017年第9期669-672,共4页Chinese Journal of Radiology

基　　金：国家自然基金面上项目（81371513）

摘　　要：目的探讨直方图分析磁敏感信号强度鉴别乳头状肾癌（pRCC）和嫌色细胞肾癌（ChRCC）的价值。方法回顾性分析经手术病理证实的13例pRCC和9例ChRCC患者资料。患者均行肾脏SWI、常规MRI平扫及增强扫描。测量直方图磁敏感信号强度参数，包括最大值、最小值、均值、中位值、偏度和峰度。采用独立样本t检验（正态分布）或Mann．Whitney秩和检验（偏态分布）比较pRCC和ChRCC间全瘤SWI参数的差异。采用ROC评价全瘤SWI参数鉴别pRCC和ChRCC的效能。结果pRCC和ChRCC磁敏感信号强度的最小值、均值、中位值、偏度差异有统计学意义（P均〈0．05），最大值、峰度差异无统计学意义（P均〉0．05）。肾脏直方图磁敏感信号强度参数中，均值鉴别pRCC和ChRCC的ROC下面积最大（0．80）；最小值鉴别诊断的敏感度最高（84．62％）；偏度的特异度最高（100．00％）．结论盲方图分析磁敏感信号强度有助于答别DRCC和ChRCC。Objective To evaluate the feasibility of histogram analysis of susceptible signal intensity in differentiating papillary （pRCC） from chromophobe renal cell carcinoma（ChRCC）. Methods Thirteen cases with pRCC and 9 cases with ChRCC, who underwent susceptible-weighted imaging（SWI）, MR common scanning and enhancement, were assessed retrospectively. The histogram parameters of susceptible signal intensity were measured, including maximum, minimum, mean, median, skewness and kurtosis. The independent samples t test（normal distribution） and Mann-Whitney rank sum test（skewed distribution） were used to compare the differences in SWI parameters between pRCCs and ChRCCs. Receiver operating characteristic curve was used to evaluate the efficiency of the whole-tumor SWI parameters in differentiating pRCCs from ChRCCs. Results The significant differences of the minimum, mean, median and skewness between pRCCs and ChRCCs were present（P〈0.05）, and there was no significant differences in maximum and kurtosis between between pRCCs and ChRCCs（P〉0.05）. In all the histogram parameters, the area of ROC curve of mean value was largest（O.80）. The sensitivity of minimum value （84.62%） was the highest and and the specificity of skewness（100.00%） was the highest. Conclusion Histogram analysis of susceptible signal intensity can help differentiate pRCCs from ChRCCs.

关 键 词：肾肿瘤 磁共振成像 直方图 

分 类 号：R445.2[医药卫生—影像医学与核医学] R737.11[医药卫生—诊断学]