高压氧对跟骨骨折合并糖尿病患者术后的临床效果观察  

Observation on the clinical effects of hyperbaric oxygen on the patients with calcaneal fracture complicated with diabetes mellitus following surgery

作　　者：李芸香 高巧平[1] 霍雪臣[2] 

机构地区：[1]烟台市烟台山医院,山东省烟台264000 [2]烟台毓璜顶医院

出　　处：《中华航海医学与高气压医学杂志》2017年第4期301-304,共4页Chinese Journal of Nautical Medicine and Hyperbaric Medicine

摘　　要：目的探讨高压氧对跟骨骨折合并糖尿病患者术后血糖控制及切口愈合的影响。方法选取2015年8月至2016年8月人院的跟骨骨折合并糖尿病患者60例，按患者所在病区分为高压氧组和对照组，各30例。对照组术后进行常规治疗护理（如抬高患肢、控制血糖、消肿、促进骨质愈合等），高压氧组在常规治疗护理的基础上增加高压氧治疗，观察并比较2组患者术后血糖控制情况及术后2周切口组织愈合情况。结果高压氧组术后第1天空腹血糖及糖化血红蛋白水平与对照组比较差异无统计学意义（P〉0．05）。术后第3天、第7天、第10天空腹血糖[高压氧组分别为（5．5±1．1）mmol／L、（5．4±1．2）mmol／L、（5．2±1．2）mmol／L，对照组分别为（7．6±0．7）mmo]／L、（7．4±0．9）mmol／L、（7．5±0．9）mmol／L]、餐后2h血糖[高压氧组分别为（8．4±1．1）mmol／L、（7．9±1．2）mmoL／L、（8．2±1．2）mmol／L，对照组分别为（10．5±1．1）mmol／L、（10．4±1．2）mmol／L、（10．9±1．2）mmol／L]及术后7d糖化血红蛋白[高压氧组为（6．7±0．4）％、对照组为（7．3±O．6）％]高压氧组明显低于对照组，差异均有统计学意义（P〈0．01）。高压氧组术后2周伤口愈合的有效率明显高于对照组，差异有统计学意义（P〈0．05）。结论跟骨骨折合并糖尿病患者术后应用高压氧治疗能有效地控制血糖，促进切口愈合。Objective To investigate the clinical effects of hyperbaric oxygen on the control of serum glucose and healing of incision in the patients with calcaneal fracture complicated with diabetes mellitus following surgery. Methods Sixty cases of calcaneal fracture complicated with diabetes mellitus hospitalized from August 2015 to August 2016 were designated as the HBO group and the control group, in accordance with different wards designated, and each group consisted of 30 cases. The patients in the control group were given conventional postsurgical treatment and nursing, such as elevation of the affected limb, control of blood glucose, repercussion and promotion of bone healing, while the patients in the HBO group received HBO therapy, in addition to conventional therapy and nursing. Serum glucose level and healing of incision 2 weeks after surgery were closely observed and compared between the patients of the 2 groups. Results There was no statistical significance in the level of fasting blood glucose and glycosylated hemoglobin for the patients of the HBO group on the first day after surgery, as compared with those of the control group （ P 〉 0.05 ）. Fasting blood glucose levels of the HBO group on the third, seventh and tenth days after surgery were respectively （5.5± 1.1 ） mmol/L, （ 5.4 ± 1.2） mmol/L and （5.2 ± 1.2） mmol/L, while those of the control group were （ 7.6 ±0. 7 ） mmol/L, （7. 4 ±0. 9 ） mmol/L and （7.5 ±0. 9 ） mmol/L respectively. Blood glucose levels 2 hours after meal for the HBO group were respectively （ 8.4 ± 1. 1 ） mmol/L, （ 7. 9±1. 2 ） mmol/L and （ 8.2 ±1.2）mmol/L, while those for the control group were （ 10.5 ± 1. 1 ） mmol/L, （ 10.4 ± 1.2） mmol/L and （10.9 ± 1.2） mmol/L respectively. Glycosylated hemoglobin level for the patients of the HBO group on the seventh day after surgery was （6.7 ± 0.4） % , while that of the control group was （7.3± 0.6） %, which was obviously higher than that of the observation group. Statistical s

关 键 词：高压氧 糖尿病患者 跟骨骨折 血糖 切口愈合 

分 类 号：R587.1[医药卫生—内分泌] R687.3[医药卫生—内科学]