清肺汤联合西药治疗小儿支原体肺炎痰热闭肺证临床观察  

Clinical Observation of Qingfei Tang Combined with Western Medicine in Treating Mycoplasma Pneumonia of Phlegm-Heat Obstructing in Lung Syndrome in Children

作　　者：莫文辉 祝秀芳 叶青 张继平[4] 

机构地区：[1]佛山市禅城区中心医院,广东佛山528000 [2]佛山市禅城区环市医院,广东佛山528000 [3]佛山市南海区第四人民医院,广东佛山528211 [4]南方医科大学附属佛山医院,广东佛山528000

出　　处：《新中医》2017年第9期102-104,共3页New Chinese Medicine

基　　金：佛山市医学类科技攻关项目(2015AB001561)

摘　　要：目的:观察中西医结合治疗小儿支原体肺炎痰热闭肺证的临床疗效。方法:选取112例支原体肺炎痰热闭肺证患儿,采用随机数字表法分为常规组和联合组各56例。常规组给予止咳化痰、解热等对症处理,联合组在上述用药基础上加用清肺汤。结果:常规组治疗总有效率82.1%,联合组治疗总有效率98.2%,2组比较,差异有统计学意义(P<0.01)。联合组的退热时间及咳嗽、肺部啰音消失时间均短于常规组(P<0.01)。治疗后,2组中医证候积分均较治疗前降低(P<0.01);联合组的中医证候积分比常规组下降更明显(P<0.01)。常规组不良反应发生率25.0%,联合组不良反应发生率32.1%,2组比较,差异无统计学意义(P>0.05)。结论:清肺汤联合西药治疗小儿支原体肺炎,临床疗效确切,可迅速改善患儿发热、咳嗽及肺部啰音等症状体征,不良反应未增加。Adjective： To observe the clinical effect of integrated Chinese and western medicine therapy in treating mycoplasma pneumonia of phlegm-heat obstructing in lung syndrome in Children. Methods： Selected 112 children with mycoplasma pneumonia of phlegm-heat obstructing in lung syndrome, and divided them into the routine group and the combination group being 56 cases in each, according to the random table method. The routine group was given the appropriate treatment of relieving cough, dissipating phlegm and defervescence, while the combination group was given Qingfei tang based on the treatment of the routine group. Results： The total effective rate was 82.1% and 98.2% in the routine group and the combination group respectively, the difference being significant（P〈0.01）. Defervescence time, time of cough and pulmonary rale disappearance in the combination group were all shorter than those in the routine group（P〈0.01）. After treatment, Chinese medicine syndrome scores of the two groups were both lower than those before treatment（P〈0.01）, and decrease of scores in the combined group was more obvious than that of the routine group（P〈0.01）. Incidence of adverse reaction was 25.0% in the routine group and was 32.1% in the combined group, the difference being no significance（P〈0.05）. Conclusion： Qingfei tang combined with western medicine has accurate clinical effect in treating mycoplasma pneumonia in Children, which can improve fever, cough and pulmonary rale without increase of adverse reaction.

关 键 词：支原体肺炎 小儿 痰热闭肺证 中西医结合疗法 清肺汤 阿奇霉素注射液 

分 类 号：R563.1[医药卫生—呼吸系统]