前外侧入路治疗髋关节置换术患者的疗效及对血清CRP,IL-6,D-二聚体水平的影响分析  

Clinical Effect of Anterolateral Approach for Patients with Hip Arthroplasty and Effect on Serum CRP,IL-6 and D-Dimer Levels

作　　者：李军 赵广跃 孙强 祝勇刚 薛宝宝 

机构地区：[1]第四军医大学第一附属医院骨科,陕西西安710032

出　　处：《现代生物医学进展》2017年第24期4684-4687,共4页Progress in Modern Biomedicine

基　　金：陕西省科技攻关项目(2006K14)

摘　　要：目的:探讨前外侧入路治疗髋关节置换术患者的疗效及对血清C-反应蛋白(CRP)、白介素-6(IL-6)、D-二聚体水平的影响。方法:选择2013年2月~2015年1月经由我院诊治的102名人工髋关节置换术患者,均征求患者的意愿分为观察组和对照组。对照组54例通过常规的入路方式进行髋关节置换术,观察组48例采用前外侧入路方式进行髋关节置换术。手术前后比较两组患者的血清CRP、IL-6和D-二聚体水平,并通过随访比较两组患者的疗效。结果:治疗后,观察组患者的总有效率显著高于对照组(P<0.05),两组患者的血清CRP、IL-6及D-二聚体在手术后12 h时升高,在7 d和14 d时,逐渐下降。观察组患者血清CRP、IL-6及D-二聚体水平在术后12 h、7 d和14 d均明显低于对照组(P<0.05)。结论:前外侧入路对髋关节置换术患者的临床疗效较常规入路方式更显著,且可有效降低血清CRP、IL-6和D-二聚体水平,更加有利于患者的术后恢复。Objective：To study Clinical Effect of Anterolateral Approach ofor the Patients with Hip Arthroplasty and the effect on the serum CRP,IL-6,D-Dimer in levels.Methods：102 Patients with Hip Arthroplasty who received therapy from February 2013 to January 2015 in our hospital,Patients were asked to be divided into observation group and control group.Among them,the control group of 54 cases,through the conventional approach to hip arthroplasty;48 cases of observation group.Serum CRP,IL-6 and D-dimer levels were compared between the two groups before and after surgery,and the efficacy of the two groups was compared by follow-up.Results：After treatment,the total effective rate of the observation group was significantly higher than that of the control group（P〈0.05）,Serum CRP,IL-6 and D-dimers increased in both groups at 12 h after surgery and decreased gradually at 7 and 14 days.The levels of serum CRP,IL-6 and D-dimer in the observation group were significantly lower than those in the control group at 12 h,7 d and 14d（P〈0.05）.Conclusion：The clinical effect of the anterolateral approach on hip arthroplasty is more significant than that of conventional approach,and can effectively reduce the levels of serum CRP,IL-6 and D-dimer,and is more favorable for postoperative recovery.

关 键 词：前外侧入路 髋关节置换术 C反应蛋白 白介素-6 D-二聚体 

分 类 号：R614[医药卫生—麻醉学] R687[医药卫生—外科学]