角调音乐疗法结合柴胡加龙骨牡蛎汤加减治疗气郁质失眠48例临床观察  

Clinical Observation on 48 Cases of Insomnia of Qi Stagnation Type Treated by Jue Tone(角调) Music Combined with Chaihu Jia Longgu Muli Tang( 柴胡加龙骨牡蛎汤)

作　　者：张莺[1] 沈叶静 胡炜[1] 涂毅萍[1] 韩德雄[1] 

机构地区：[1]浙江中医药大学附属第三医院 [2]浙江中医药大学第三临床医学院

出　　处：《中医杂志》2017年第18期1577-1580,共4页Journal of Traditional Chinese Medicine

基　　金：浙江省中医药科技计划(2014ZA061;2012ZB073);第四批浙江省重点科技创新团队(2013TD15)

摘　　要：目的评价角调音乐疗法结合柴胡加龙骨牡蛎汤加减治疗气郁质失眠的疗效。方法将139例气郁质失眠患者随机分为综合组48例、中药组46例、西药组45例。治疗组采用角调音乐疗法结合柴胡加龙骨牡蛎汤加减口服治疗,中药组口服柴胡加龙骨牡蛎汤加减方药,西药组口服唑吡坦片,同时三组均进行情志疏导和健康指导。治疗4周后评价临床疗效,治疗前后采用中医体质分类与判定自测表(CCMQ)和匹兹堡睡眠质量指数(PSQI)进行评分,同时评价治疗的安全性。结果综合组总有效率(95.83%)高于中药组(82.61%)和西药组(80.00%)(P<0.05或P<0.01)。与治疗前比较,综合组和中药组治疗后CCMQ、PSQI评分明显降低,西药组PSQI评分亦降低(P<0.05)。综合组治疗后CCMQ、PSQI评分低于中药组和西药组(P<0.05或P<0.01)。中药组治疗后CCMQ评分亦低于西药组(P<0.05),而PSQI评分差异无统计学意义(P>0.05)。各组均无不良事件发生。结论角调音乐疗法结合柴胡加龙骨牡蛎汤加减口服能改善气郁质失眠患者气郁状态和睡眠质量,且安全性好。Objective To evaluate the efficacy of Jue Tone music combined with Chaihu Jia Longgu Muli Tang（ 柴胡加龙骨牡蛎汤,CLMT） in treating insomnia of Qi stagnation type. Methods Totally 139 patients with insomnia of Qi stagnation type were randomized into comprehensive group（ 48 cases）,Chinese medicine group（ 46 cases）and western medicine group（ 45 cases）. The comprehensive group was treated by Jue Tone music combined with oral modified CLMT,Chinese medicine group was given oral modified CLMT alone,and western medicine group was administered with oral zolpidem tablets. All these three groups were given emotional counseling and health guidance at the same time. The clinical efficacy was evaluated after 4-week treatment with Constitution in Chinese Medicine Questionnaire（ CCMQ） and Pittsburgh Sleep Quality Index（ PSQI）. The treatment safety was also evaluated at the same time. Results The total effective rate in the comprehensive group（ 95. 83%） was higher than that in Chinese medicine group（ 82. 61%） and western medicine group（ 80. 00%）（ P 0. 05 or P 0. 01）. Compared with those before treatment,after treatment CCMQ and PSQI scores in the comprehensive group and Chinese medicine group significantly decreased,and the PSQI score of western medicine group also decreased（ P 0. 05）. CCMQ and PSQI scores in the comprehensive group were lower than those in Chinese medicine group and western medicine group（ P 0. 05 or P 0. 01）. After treatment,the CCMQ score in Chinese medicine group was also lower than that in western medicine group（ P 0. 05）,but there was no significant difference in PSQI score between the two groups（ P 0. 05）. No adverse events occurred in each group. Conclusion Jue Tone music combined with oral modified CLMT could improve Qi stagnation status and sleep quality of the patients with insomnia of Qi stagnation type with good safety.

关 键 词：失眠 角调 音乐疗法 气郁质 柴胡加龙骨牡蛎汤 睡眠质量 

分 类 号：R256.23[医药卫生—中医内科学]