特效解毒剂的临床应用  

The clinical application of specific antidotes

作　　者：郝凤桐[1] 

机构地区：[1]首都医科大学附属北京朝阳医院,北京100020

出　　处：《职业卫生与应急救援》2017年第1期23-27,共5页Occupational Health and Emergency Rescue

摘　　要：中毒性疾病的治疗在对症支持治疗的基础上,主要通过改变毒物代谢动力学和改变毒效学两条途径来实现。通过分别概述急性有机磷杀虫剂中毒、中毒性高铁血红蛋白血症、抗凝血杀鼠剂中毒、铅中毒、汞中毒的特效解毒剂治疗效果,对特效解毒剂的临床应用现况做了分析和探讨。The therapeutic principle of the poisoning diseases is mainly through two ways involved in change of toxicokinetics and toxicodynamics of specific chemical, except for the supportive symptomatic treatment. This article summarized the common used antidotes in China against acute organophosphorus pesticide poisoning,toxic methemoglobinemia,anti-clotting agent poisoning,rodenticide poisoning,lead poisoning,and mercury poisoning. The experiences and notes of clinical application of such antidotes were present.

关 键 词：特效解毒剂 有机磷杀虫剂 高铁血红蛋白血症 杀鼠剂 铅中毒 汞中毒 

分 类 号：R979.3[医药卫生—药品]