质谱双探针法对食品中N-亚硝胺化合物的全检测  

Determination of N-nitrosamine compounds in food by using double-ion probe method of electron impact mass spectrometry

作　　者：刘秋华[1] 杨艳 周再春[1] 成奋民[1] 袁晟[2] 田俐[1] 

机构地区：[1]湖南科技大学化学化工学院理论有机化学与功能分子教育部重点实验室,湖南湘潭411201 [2]湘潭市疾病预防控制中心,湖南湘潭411100

出　　处：《湖南科技大学学报（自然科学版）》2017年第2期78-84,共7页Journal of Hunan University of Science And Technology：Natural Science Edition

基　　金：国家自然科学基金资助项目(21372069;21602054);教育部新世纪优秀人才支持计划资助项目(NCET-13-0784)

摘　　要：食品中亚硝胺化合物的种类达300种,当前的亚硝胺检测国标只检测代表性的4种亚硝胺化合物.选择亚硝胺类化合物在EI源质谱中电离出的亚硝酰胺基(N2O)和亚硝酰(NO)2个独特碎片离子作双探针信号,以市售腊肉为检测对象,探索出一种亚硝胺类化合物全检测的方法,大幅度减少了现有国家标准对食品中亚硝胺类化合物的漏检.该检测方法原理简单、实验操作方便、测试成本低.There are over 300 N-nitrosamine compounds found in food, but the current national standards . N-nitrosamine compounds can two unique fragment ions, nitroso amide （N2O） and nitrosyl （NO）, in electron impact be ionized and produce （EI） mass spectrometry ionization, and this property is used to determine the existence of nitrosamine compounds and quantify these compounds by selecting the two ions as double-probe signals. The commercially available preserved meat was selected as test objects. A method of determination of N-nitrosamine compounds in food was explored. This method can greatly reduce the missed detection of nitrosamine compounds existing in food. The method is simple in principle and the experiment operation involved is convenient, it greatly cut down the cost of testing.

关 键 词：N-亚硝胺 电子轰击质谱 离子探针 食品安全 

分 类 号：O656.3[理学—分析化学]