11项化验指标对肺部感染痰热壅肺证的诊断意义  

Diagnostic Significance of Eleven Indicators in Pneumonia Patients with Syndrome of Phlegm-heat Obstructing Lung

作　　者：沈威 方晓磊[1] 赵妍[1] 刘福生[1] 郝瑞福[1] 

机构地区：[1]北京中医药大学,北京100161

出　　处：《成都中医药大学学报》2017年第3期83-86,共4页Journal of Chengdu University of Traditional Chinese Medicine

基　　金：北京中医药大学自主选题资助项目(2015-JYB-JSMS122)

摘　　要：目的:探讨11项化验指标在肺部感染痰热壅肺证诊断中的意义。方法:检测60例肺部感染痰热壅肺证患者的血白细胞(WBC)、中性粒细胞计数(N#)、C-反应蛋白(CRP)、血小板(PLT)、氧分压(PO2)、二氧化碳分压(PCO2)、凝血酶原时间(PT)、部分凝血活酶时间(APTT)、血红蛋白(HGB)、红细胞压积(HCT)和血清白蛋白(ALB)等11项化验指标。对其检测值水平进行统计分析。结果:在感染方面,CRP的阳性率最高,N#与WBC相近。其余化验指标依次在营养、呼吸衰竭及凝血方面表现出从高到低的阳性率。其中,ALB在营养方面的敏感性更高;呼吸衰竭方面以单纯换气功能障碍为主;凝血功能的异常无明显特征性。结论:11项化验指标能够从多方面对肺部感染痰热壅肺证的患者进行了分析和评估。其中CRP、HGB、ALB和PO2可能与证候存在相关性。Objective： To explore the diagnostic significance of the 11 blood indicators to pneumonia with the syndrome of phlegm- heat obstructing lung. Methods： The levels of white blood cell （WBC）, neutrophil count （N#）, C-reactive protein （CRP）, plate- let （ PLT）, partial pressure of oxygen （ PO2 ）, partial pressure of carbon dioxide （ PCO2 ）, prothrombin time （ PT）, activated partial thromboplastin time （APTT）, hemoglobin （HGB）, hematocrit （HGT） and albumin （ALB） were measured in 60 pneumonia pa- tients with the syndrome of phlegm-heat obstructing lung. Then we explored the clinical value of the 11 blood examination indicators to the pneumonia patients with the syndrome of phlegm-heat obstructing lung by regression analysis method. Results： CRP played the best correlation with pneumonia patients with the syndrome of phlegm-heat obstructing lung, while N# was similar with WBC in indicators related to infection. The other indicators showed the positive rate from high to low on nutrition, respiratory failure and blood coagula- tion, respectively. Additionally, ALB showed more sensitive on nutrition aspect, while only ventilatory disorder on oxygenation as- pect. However there is no obvious characteristic of dysfunctions of the blood clotting. Conclusions： The eleven indicators in this re- search showed a comprehensive evaluation significance from infection, nutrition, respiratory and blood coagulation to pneumonia with the syndrome of phlegm-heat obstructing lung. The positive rate of CRP, HGB, ALB and PO2 may had correlation with the syndrome.

关 键 词：肺部感染 痰热壅肺证 C-反应蛋白 化验指标 

分 类 号：R563.1[医药卫生—呼吸系统] R256.1[医药卫生—内科学]