巴东冬凌草二萜成分的研究  

Diterpenoids From Badong Rabdosia rubescens (Hemsl.) Hara

作　　者：舒佳为 袁芳 文楚毛 杨光忠[3] Shu Jiawei Yuan Fang Wen Chumao Yang Guangzhong(College of Environment and Bio -- resources, Dalian Minzu University, Dalian 116600, China College of Biomedical Engineering, South Central University for Nationalities, Wuhan 430074, China National Demonstration Center for Experimental Ethnopharmacology Education, South--Central University .for Nationalities, Wuhan 430074, China)

机构地区：[1]大连民族大学环境与资源学院,辽宁大连116600 [2]中南民族大学生物医学工程学院,湖北武汉430074 [3]中南民族大学民族药学国家级实验教学示范中心,湖北武汉430074

出　　处：《绿色科技》2017年第18期216-218,共3页Journal of Green Science and Technology

基　　金：国家自然科学基金项目(编号:31370379)

摘　　要：利用溶剂提取法,正、反相硅胶柱和半制备高效液相色谱法对巴东冬凌草乙酸乙酯提取物进行了分离纯化,从中分离得6个二萜化合物,并根据理化性质和现代波谱技术对其进行了结构鉴定,其结构分别鉴定为:冬凌草甲素(1)、lasiodin(2)、neolaxiflorin U(3)、hubeirubesin K(4)、hubeirubesin I(5)、epinodosinol(6)。其中化合物3~6为首次从该地区的植物中分离得到。The chemical constituents of Badong Rabdosia rubescens were isolated and purified by solvent extraction method, the normal and reverse phase silica gel column chromatography and semi--preparative HPLC. Their structures were elucidated on the basis of chemical and spectroscopic analysis. Six diterpenoids were isolated from the ethyl acetate extract of Rabdosia rubescens and were identified as oridonin （1） lasiodin （2） neolaxiflorin U （3） hubeirubesin K （4） hubeirubesin I （5） epinodosinol （6） Compound 3--6 were isolated from Badong Rabdosia rubescens for the first time.

关 键 词：巴东冬凌草 化学成分 二萜 

分 类 号：R927[医药卫生—药学]