病态窦房结综合征患者脑梗死危险因素分析  

Analysis of risk factors of cerebral infarction in patients with sick sinus syndrome

作　　者：张鹤萍[1] 彭晖[1] 吴永全[1] 马文英[1] ZHANG Heping PENG Hui WU Yongquan MA Wenying(Department of Cardiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China)

机构地区：[1]首都医科大学附属北京友谊医院心内科,100050

出　　处：《心肺血管病杂志》2017年第8期645-647,共3页Journal of Cardiovascular and Pulmonary Diseases

摘　　要：目的:探讨病态窦房结综合征(SSS)患者脑梗死的危险因素。方法:336例SSS患者中,SSS合并脑梗死组83例,SSS不合并脑梗死组253例(对照组),回顾性分析脑梗死发生的危险因素。结果:SSS合并脑梗死组年龄明显高于对照组(P<0.05),且患病率随着年龄增加而明显增加;SSS合并脑梗死组吸烟、有高脂血症史、合并冠心病、既往有心力衰竭发作史及不规律服用阿司匹林的比例明显高于对照组(P<0.05)。Logistic回归分析显示:年龄、吸烟、高脂血症史及不规律服用阿司匹林是脑梗死发生的危险因素[OR=1.065(95%CI:1.029~1.102),2.128(95%CI:1.209~3.745),1.740(95%CI:1.021~2.966),1.962(95%CI:1.147~2.863)。结论:年龄、吸烟、高脂血症史及不规律服用阿司匹林是发生脑梗死的危险因素。Objective： To discuss the risk factors in sick sinus syndrome（ SSS） patients of getting cerebral infarction（ CI）. Methods： 336 SSS patients were included in this study,of which 83 with CI and 253 without CI as control. The risk factors of getting CI in SSS patients were analyzed retrospectively. Results： The age in SSS patients with CI was significantly higher than the control group（ P〈0. 05）,and morbidity rate rose as age grew. The proportion of smoking,history of hyperlipidemia,coronary artery disease（ CAD）,history of heart failure and irregular aspirin treatment in SSS patients with CI were significantly higher than those in control group（ P〈0. 05）. Age,smoking,history of hyperlipidemia and irregular aspirin treatment were risk factors of CI in multivariate regression analysis[OR（ 95% CI） 1. 065（ 1. 029-1. 102）,2. 128（ 1. 209-3. 745）,1. 740（ 1. 021-2. 966）,1. 962（ 1. 147-2. 863）. Conclusion： Age,smoking,history of hyperlipidemia and irregular aspirin treatment are risk factors of CI in patients with SSS.

关 键 词：病态窦房结综合征 脑梗死 危险因素 

分 类 号：R54[医药卫生—心血管疾病]