非离子型对比剂在CT增强中过敏反应的预防和处理  

PREVENTION AND TREATMENT OF ALLERGIC EFFECTS CAUSED BY CT CONTRAST ENHANCEMENT USING NON-IONIC CONTRAST MEDIA

作　　者：王雅祥 白丽英 杨德久 文世强 Wang Yaxiang Bai Liying Yang Dejiu et al(Second People＇s Hospital of Fengrun District, Tangshan 064000, Chin)

机构地区：[1]河北省唐山市丰润区第二人民医院影像科,064000 [2]华北理工大学附属医院影像科 [3]哈尔滨医科大学

出　　处：《中国煤炭工业医学杂志》2017年第9期1061-1063,共3页Chinese Journal of Coal Industry Medicine

摘　　要：目的非离子型对比剂在CT增强中应用越来越广泛,探讨其过敏反应的发生相关因素,制定科学合理的预防和救治措施。方法回顾性分析该院自2016年1月—2017年6月CT增强病例3 326例,其中,男1 903例,女1 423例。药物为非离子型对比剂碘海醇(欧苏),浓度为350mg/ml,剂量50~100ml。高压造影注射装置为江阴市东佳医疗器械有限公司DJ2000A2,注射速度为2.5~3ml/s。CT设备为TOSIBA Aquilion 16多层螺旋CT机。结果轻度过敏反应86例,占2.58%,中度过敏反应1例,占0.03%。重度过敏反应1例,占0.03%。结论非离子对比剂安全可靠,但仍有少数患者发生过敏反应,重度过敏反应尽管发生率很低,但它危及患者生命安全,必须足够重视,只有做好对比剂过敏反应的预防和处理,才能保障患者用药的安全。Objective To explore the relative factors of affecting allergic induced by Non-ionic contrast media,and to summarize our experiences on preventing and treating.Methods In the period from January 2016 to June 2017,our department had treated 3326 patients using contrast enhanced CT.Among them,1903 were males and 1423 were females.Lohexol was used as the contrast enhancing media.The effective component＇s concentration was 350mg/ml.The dose of contrast media was 50-100 ml.The high pressure injector DJ2000A1 was supplied by Dongjia Medical Instrument Ltd located in Jiangyin City.The injection speed was 2.5-3ml/s.CT Machine is TOSHIBA Aquilion 16 multistory helical CT（MSCT）.Results In the 3326 patients,86 experienced light allergic effect,accounting for 2.58%;one experienced moderate allergic effects,accounting for 0.03% and another experienced severe allergic effects,accounting for 0.03%.Conclusion Non-ionic contrast media iohexol is a very safe medicine.Nevertheless,there are still a small portion of patients suffering from allergic effects.Some severe cases may be life threatened.It is critically important when using such media to take careful allergic testing and set up prevention and treatment plan.

关 键 词：CT增强扫描 对比剂 过敏反应 预防与治疗 

分 类 号：R445[医药卫生—影像医学与核医学]