T2~*mapping定量评估早期骨关节炎半月板与软骨的相关性  

Quantitative assessment of the correlation between meniscus and cartilage in early osteoarthritis with T2~* mapping

作　　者：梁学恒 杨全[1] 余洁[1] 文兵[1] LIANG Xue-heng YANG Quan YU Jie WEN Bin.(Department of Radiology, Yongchuan Hospital of Chongqing Medical University, Yongchuan 402160, Chongqing, CHINA)

机构地区：[1]重庆医科大学附属永川医院放射科,重庆402160

出　　处：《海南医学》2017年第16期2631-2634,共4页Hainan Medical Journal

摘　　要：目的利用T2*mapping评估早期膝关节骨性关节炎(OA)的软骨与半月板并分析半月板退变与软骨损伤的相关性。方法收集2016年8~11月在重庆医科大学附属永川医院骨科就诊的65例早期OA患者,均行常规MR、多回波梯度回波T2*mapping扫描。并测量所有患者内、外侧半月板损伤在Stoller分级中软骨与半月板T2*值。结果内侧半月板损伤中,MM 1级组T2*值[(10.33±2.82)ms]高于MM 0级[(8.95±1.73)ms],MM 2、3级组T2*值[(13.31±2.27)ms]均高于MM 0级组、MM 1级组,差异均有统计学意义(P<0.05);外侧半月板损伤中,MM 1级组T2*值[(10.63±2.58)ms]高于MM 0级[(8.65±2.61)ms],MM 2、3级组T2*值[(13.59±2.41)ms]均高于MM 0级组、MM 1级组,差异均有统计学意义(P<0.05);内侧半月板损伤中,2、3级组股骨内侧踝(MFC)与胫骨内侧(MT)的T2*值均高于0级组、1级组的T2*值,外侧半月板损伤中,2、3级组胫骨外侧(LT)高于0级、1级组软骨单元T2*值,差异均有统计学意义(P<0.05);内侧半月板T2*值与内侧股骨髁、内侧胫骨软骨单元T2*值呈正相关(r=0.45,r=0.56);外侧半月板T2*值与外侧胫骨软骨单元T2*值呈正相关(r=0.40)。结论 T2*mapping能够定量监测OA半月板退变,OA半月板损伤与邻近软骨损伤呈正相关。Objective To assess the correlation between meniscus and cartilage in early osteoarthritis（OA）with T2^＊ mapping. Methods A total of 65 patients with early OA, who admitted to Department of Radiology of Yongchuan Hospital of Chongqing Medical University and underwent routine conventional MR sequences and mutil-echo gradient echo sequence for T2^＊ mapping, were selected as the research subjects. The T2^＊ values of menicus and cartilage in Stoller grade score system for internal and lateral meniscus injury of the patients were measured. Results For medial meniscal tear, the T2^＊ value of medial meniscus（MM） 1 group was（10.33 ± 2.82） ms, which was significantly higher than（8.95±1.73） ms of MM 0 group（P〈0.05）. The T2^＊ value of MM 2 and 3 group was（13.31±2.27） ms, which was significantly higher than the T2^＊ value of MM 0 and MM 1 group（P〈0.05）. For lateral meniscal tear, the T2^＊ value of MM1 group was（10.63±2.58） ms, which was significantly higher than（8.65±2.61） ms of MM 0 group（P〈0.05）. The T2^＊value of MM 2 and 3 group was（13.59±2.41） ms, which was significantly higher than MM 0 and MM 1 group（P〈0.05）.For medial meniscal tear, the T2^＊ value of medial femoral condyle（MFC） and medial tibial（MT） in 2 and 3 grade was significantly higher than that in 0 grade and 1 grade; For lateral meniscal tear, the T2^＊ value of lateral meniscus（LT） in 2 and3 grade was significantly higher than that in 0 grade and 1 grade（P〈0.05）. The T2^＊ value of the medial meniscus was positively correlated with the T2^＊ values of the MFC and MT（r=0.45, r=0.56）; The T2^＊ value of the lateral meniscus（LM）was positively correlated with the T2^＊ value of the LT（r=0.40）. Conclusion T2^＊ mapping can quantitatively monitor the meniscal degeneration in early OA. There is a positive correlation between meniscal tear and adjacent to cartilage damage.

关 键 词：T2^＊mapping 骨关节炎 软骨 半月板 

分 类 号：R684.3[医药卫生—骨科学]