福建省0～3岁婴幼儿儿心量表筛查法的应用及ROC曲线评价  

Application and the evaluation of the ROC curve among 0 to 3 years old infant of neuropsychological examination screening in Fujian province

作　　者：欧萍[1] 卢国斌[1] 王艳霞[1] 刘桂华[1] 钱沁芳[1] 林元[1] 杨式薇[1] 李国凯[1] 杨闽燕[1] 余秋娟[1] 

机构地区：[1]福建医科大学附属福建省妇幼保健院,福州350001

出　　处：《中国妇幼卫生杂志》2017年第4期9-13,31,共6页Chinese Journal of Women and Children Health

基　　金：中国疾病预防控制中心妇幼保健中心合生元母婴营养与健康研究基金资助项目(2015FYH007);中华预防医学会公共卫生应用研究与疫苗可预防疾病科研项目(20101303);福建省科技计划社会发展重点项目(2012Y0010);福建省自然科学基金资助项目(2016J01490)

摘　　要：目的评估0~3岁婴幼儿儿心量表筛查法的应用效果。方法分层随机选取2015-2016年就诊于福建省妇幼保健院儿童心理保健科门诊0~3岁婴幼儿609例,以Gesell发育量表为金标准,对入选婴幼儿分别行Gesell发育量表诊断和儿-心量表筛查法测验。结果在609例婴幼儿中,儿-心量表筛查法评定阳性组为247例,Gesell量表智能评定阳性组为212例。总样本及各月龄组小儿进行儿-心量表筛查法评估结果的灵敏度分别为91.0%、87.5%、92.6%、95.7%、92.9%、88.0%、92.0%、92.9%、87.5%;假阴性率(FNR)分别为9.0%、12.5%、7.4%、4.3%、7.1%、12.0%、8.0%、7.1%、12.5%;Kappa值分别为0.75、0.68、0.72、0.77、0.76、0.74、0.68、0.86、0.75。ROC曲线下面积(AUC)=0.827(P<0.01),95%置信区间(0.723~0.931)。结论应用0~3岁儿心量表筛查法操作较为便捷、可靠,该法部分月龄段条目进一步优化后可在福建省推广使用。Objective To evaluate the application of neuropsychological examination screening among 0 to 3 years old infant. Methods Stratification and random sampling method was used to select 609 infants with 0-3 years old from child psychological outpatient in the hospital during 2015 to 2016. The infants were tested by Gesell development and infant neuropsychological examination screening. Results Among the 609 infants, 247 infants were evaluated to the positive by neuropsychological examination screening, and 212 infants were evaluated to the positive by Gesell scale. The results of sensitivity of the total samples and every months of age groups were 91.0%, 87.5%, 92.6%, 95.7%, 92.9%, 88.0%, 92.0%, 92.9% and 87.5% respectively; False negative rate were 9.0%, 12.5%, 7.4%, 4.3% , 7.1% , 12.0% , 8.0% , 7.1% and 12.5% respectively; Kappa value were 0. 75, 0.68, O. 72, 0.77, 0.76 , O. 74, 0.68, 0.86 and 0.75 respectively. The area under the ROC curve was 0.827 （ P 〈 0.01 ） and 95% confidence interval was from 0. 723 to 0. 931. Conclusion Neuropsychological examination screening among 0-3 years old infant is convenient and reliable, and it can be used widely in Fujian province after improved.

关 键 词：儿心量表 筛查 ROC曲线 

分 类 号：R174[医药卫生—妇幼卫生保健]