双氯芬酸钠栓在经阴道取卵术中的镇痛效果观察  

Analgesic Effect of Diclofenac Sodium Suppository in Transvaginal Oocyte Retrieval

作　　者：刘振萍 黄云 刘珊珊 

机构地区：[1]赣州市妇幼保健院,江西赣州341000

出　　处：《现代医院》2017年第9期1374-1376,共3页Modern Hospitals

基　　金：赣州市指导性科技计划项目(编号:GZ2016ZSF175)

摘　　要：目的探讨双氯芬酸钠栓在经阴道取卵术中的应用及效果。方法收集我院2016年7月—2017年5月300例经阴道取卵术的患者,按照用药情况分成观察组与对照组,观察组应用双氯芬酸钠栓进行镇痛,对照组采用芬太尼联合异丙酚进行麻醉,观察两组患者经阴道取卵术中的镇痛效果及术后不良反应。结果两组患者经阴道取卵术中的镇痛效果比较,差异无统计学意义(P>0.05);对照组头晕、恶心呕吐、注射部位疼痛、呼吸抑制、舌后坠等不良反应均高于观察组,对比差异均有统计学意义(P<0.01);观察组获卵数、受精率、优质胚胎率与对照组比较,差异无统计学意义(P>0.05)。结论经阴道取卵术中应用双氯芬酸钠栓具有较为良好的镇痛效果,且不良反应少,使用方便,安全性高,值得临床应用推广。Objective To explore the effect of diclofenac sodium suppository in transvaginal oocyte retrieval. Methods 300 patients who had undergone transvaginal oocyte retrieval in our hospital from July 2016 to May 2017, were divided into the observation group and the control group based on medications. The observation group was given diclofenac sodium suppository to relieve pain and the control group was given Fentanyl combined with propofol to carry out anesthesia. Intraoperative analgesic effect and postoperative adverse reactions were observed and compared bewteen the two groups. Results There was no statistically significant difference in analgesic effect between the two groups （ P 〉 0. 05 ）. The adverse reactions of the control group like dizziness, nausea and vomiting, soreness at the injection site, respiratory depression, glossocoma were more frequent than those of the observation group and the differences are statistically significant （P 〈0. 01 ）. There was no statistically significant difference in the number of retrieved oocytes, fertilization rate and quality embryo rate between the two groups （ P 〉 0. 05 ） . Conclusion Diclofenac sodium suppository has better analgesic effect and fewer adverse reactions in transvaginal oocyte retrieval. It is easy to apply, safe and worthy of clinical application.

关 键 词：双氯芬酸钠栓 芬太尼 异丙酚 经阴道取卵术 镇痛 

分 类 号：R713.7[医药卫生—妇产科学]