肺癌患者肺部感染的易感因素与病原菌分析  

Analysis of Predisposing Factor and Pathogenic Bacteria of Lung Infection of Patients with Lung Cancer

作　　者：李广贺[1] LI Guang-he(General Medicine Department, Xincheng Branch of Zaozhuang Municipal Hospital, Zaozhuang, Shandong Province, 277800 Chin)

机构地区：[1]枣庄市立医院新城分院全科医学科,山东枣庄277800

出　　处：《世界复合医学》2017年第2期23-25,共3页World Journal of Complex Medicine

摘　　要：目的探讨引起肺癌患者肺部感染的易感因素,并对病原菌分布情况进行分析。方法对该院2015年11月—2016年10月收治的肺癌合并肺部感染患者115例临床病历资料进行回顾性分析,对肺部感染易感因素进行二分类Logistic回归分析,并对肺部感染患者送检标本病原菌检出情况进行分析。结果年龄≥60岁、有长期大量吸烟史、肿瘤细胞中高度分化、未预防性使用抗生素、微创手术方式、住院时间≥15 d、术后进行放化疗治疗为肺癌患者肺部感染的易感因素,差异有统计学意义(P<0.05);细菌鉴定结果显示115份痰液标本共检出致病菌168例,其中革兰阴性菌109例,占64.88%,病原菌中出现频率较高的为肺炎克雷伯菌、大肠埃希菌、鲍曼不动杆菌;病原菌呈现较高多重耐药性。结论临床治疗过程中针对引发肺部感染的易感因素给予相应的治疗和护理,根据病原菌分布情况有针对性的用药,有助于规范抗菌药物的合理使用,获得满意度的治疗效果。Objective To study the predisposing factor and pathogenic bacteria of lung infection of patients with lung cancer and analyze the distribution of pathogenic bacteria. Methods 115 cases of patients with lung cancer and lung infection admitted and treated in our hospital from November 2015 to October 2016 were selected and the predisposing factor of lung cancer was given the second classifi- cation and the test of pathogenic bacteria of submission specimens of lung infection patients were given the Logistic regression analy- sis. Results The age i〉60 years, long-term heavy smoking history, high differentiation in tumor cells, High differentiation in tumor cells, no predictive use of antibacterial, minimally invasive surgery, length of stay 〉 15 d and chemotherapy after surgery were the predisposing factor of lung infection of patients with lung cancer, and the differences were statistically significant （P〈0.05）, and the i- dentification results of bacteria showed that of 115 pieces of sputum samples, 168 cases with pathogenic bacteria, including 109 cases with gram negative bacteria, accounting for 64.88%, and the occurrence frequency of pathogenic bacteria from high to low was re- spectively klebsiella pneumoniae, escherichia coli and acinetobacter bauman. Conclusion In clinical treatment course, we should con- duct the corresponding treatment and nursing of predisposing factor of lung infection and targeted drug use according to the distribu- tion of pathogenic bacteria thus standardizing the rational use of antibacterial and obtaining a satisfactory treatment effect.

关 键 词：肺癌 肺部感染 易感因素 病原菌分布 

分 类 号：R4[医药卫生—临床医学]