离子色谱法测定钙镁片中钙、镁离子的含量  

Determination of the Content of Calcium and Magnesium Ion in Calcium Magnesium Tablets by Ion Chromatography

作　　者：朱荣菊[1] 王鹏[1] ZHU Rong-ju WANG Peng(Xi＇an Innovation College, Yan＇an University, Xi＇an, 710100, China)

机构地区：[1]延安大学西安创新学院,陕西西安710100

出　　处：《化学与粘合》2017年第5期389-392,共4页Chemistry and Adhesion

摘　　要：采用离子色谱法进行了钙镁片中Ca^(2+)和Mg^(2+)的含量测定,过程为:先采用盐酸将样品溶解之后,采用阳离子交换色谱柱分离,用阳离子抑制器,分别进行精密度试验,重复性试验,加样回收率试验,系统适用性试验,最后结果检测。实验结果表明Ca^(2+)和Mg^(2+)的质量浓度处于2~18mg·L^(-1)和0.4~9mg·L^(-1)之间时,具有标准的线性关系,其相关系数都接近于1;Ca^(2+)和Mg^(2+)的检出浓度为0.003mg·L^(-1)和0.015mg·L^(-1),其定量浓度为0.004mg·L^(-1)和0.002mg·L^(-1),回收率也均接近100%;实验测的5批样品中Ca^(2+)的含量分别为13.5%、14.8%、15.0%、16.3%、10.6%,Mg^(2+)的含量分别为5.2%、3.8%、4.5%、6.0%、3.9%。In order to determine the content of Ca2＋ and Mg2＋ in calcium magnesium tablets, the ion chromatography is used in this experiment. The process is as follows： firstly, the sample dissolves in hydrochloric acid, followed by the separation by cation ions exchange chromatography col-umn, and then the cation suppressor is used for the precision test, repeatability test, recovery test, system suitability test, and the final results test re-spectively. The experimental results show that when the concentration of Ca2＋ and Mg2＋ is between 2～18mg·L-1 and 0.4～9mg·L-1 respectively, a good linear relationship appeared, and the correlation coefficients are close to 1;the detectable concentration of Ca2＋ and Mg2＋ is 0.003 and 0.015mg·L-1 re-spectively, and the quantitative concentration of them is 0.004 and 0.002mg·L-1 respectively, and the recovery rate is close to 100%. In these 5 batch-es of samples, the content of Ca2＋are 13.5%, 14.8%, 15%, 16.3%and 10.6%respectively, and the content of Mg2＋ are 5.2%, 3.8%, 4.5%, 6.0%, 3.9%respectively.

关 键 词：离子色谱法 钙离子 镁离子 

分 类 号：TQ460.72[医药卫生—药物分析学]