Synthesis of 1,2,4-Triazine Compounds via Two Distinct One-Pot Domino Protocols  

作　　者：Yafeng Liu Xin Guo Dong Tang Jing Wang Ping Wu Jianwei Han Baohua Chen 

机构地区：[1]State Key Laboratory of Applied Organic Chemistry, Lanzhou University, Lanzhou, Gansu 730000, China [2]Department of Chemistry, Lishui University, Lishui, Zhejiang 323000, China

出　　处：《Chinese Journal of Chemistry》2017年第8期1222-1226,共5页中国化学（英文版）

基　　金：Acknowledgement We are sincerely grateful for sponsorship of this project by the National Natural Science Foundation of China （No. 21372102）.

摘　　要：1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot with the advantages of high functional groups tolerance, being transition metal-free, and employing environmentally friendly oxidants such as I2 and IBX. nroviding, access to the desired 1,2,4-triazine products in excellent yields.1,2,4-Triazine compounds were synthesized via two coupled domino strategies employing simple and readily available arylacetaldehydes/arylethyl alcohols as starting materials. The reactions proceed smoothly in one pot with the advantages of high functional groups tolerance, being transition metal-free, and employing environmentally friendly oxidants such as I2 and IBX. nroviding, access to the desired 1,2,4-triazine products in excellent yields.

关 键 词：TRIAZINES ALDEHYDES ALCOHOLS N-aminobenzamidines DOMINO 

分 类 号：TQ633[化学工程—精细化工] TU998.1[建筑科学—市政工程]