基于中医整体观的喉源性咳嗽各证型发病特点的流行病学研究  

Epidemiological study on clinical characteristics of syndrome types of laryngeal cough based on the holism concept of TCM

作　　者：张勉[1] 陈潇[1] 黄卓燕[1] 高阳[1] 李艺[1] 莫绍毅[1] 谢勇[2] 郑琴媛 

机构地区：[1]广西中医药大学第一附属医院,南宁市530023 [2]广西中医药大学附属瑞康医院,南宁市530023

出　　处：《实用医学杂志》2017年第18期3131-3135,共5页The Journal of Practical Medicine

基　　金：国家自然科学基金项目(编号:81260551)

摘　　要：目的对喉源性咳嗽各证型的发病特点进行研究,为喉源性咳嗽的分型诊断提供流行病学依据。方法搜集喉源性咳嗽患者的病史、临床症状、体征等资料,填写调查问卷表。结果 (1)4组证型中,卫表不固、禀质特异型与风邪犯肺型比较,其发患者数差异无统计学意义(P>0.05),其余两组间比较差异均有统计学意义(均P<0.05)。(2)对各证型的发病时间进行分析,虚火旺型差异无统计学意义(P>0.05),余各证型差异均有统计学意义(均P<0.05)。(3)对各证型的病程进行分析,脾虚痰浊型与阴虚火旺型比较,差异无统计学意义(P>0.05),其余两组间比较差异均有统计学意义(均P<0.05)。(4)对各证型的病情进行分析,风邪犯肺型与脾虚痰浊型及脾虚痰浊型与卫表不固、禀质特异型比较,差异有统计学意义(P<0.05),其余两组间比较差异均无统计学意义(均P>0.05)。(5)对各证型关于鼻变态反应及眼变态反应伴随发生率进行分析,差异均无统计学意义(均P>0.05)。(6)对痰进行分析,风邪犯肺型与阴虚火旺型比较,差异无统计学意义(P>0.05),其余两组间比较差异均有统计学意义(均P<0.05)。(7)对异物感进行分析,风邪犯肺型与卫表不固、禀质特异型及脾虚痰浊型与阴虚火旺型比较差异无统计学意义(P>0.05),其余两组间比较差异均有统计学意义(均P<0.05)。结论喉源性咳嗽以卫表不固、禀质特异型与风邪犯肺型最常见,其次为脾虚痰浊型,阴虚火旺型最少见。风邪犯肺型咳嗽以晚上为主,病程多<1个月,伴有痰,无咽异物感或偶有咽异物感,日常生活不受影响或稍受影响。卫表不固、禀质特异型咳嗽以上午为主,病程多在3个月~1年,少痰或无痰,无咽异物感或偶有咽异物感,日常生活不受影响或稍受影响。阴虚火旺型咳嗽不定时,病程多>1年,伴有痰,有咽异物感,日常生活不受影响或受严重影响。脾虚痰浊型咳嗽以上午为主,病�Objective To study the clinical characteristics of syndrome types of laryngeal cough, in order to provide an epidemiology basis for classification diagnosis. Methods Medical history, clinical signs and symp- toms of patients with laryngeal cough were collected. And questionnaire survey was carried out. Results （ 1 ） Of the 4 syndrome types, compared with wind evil invading lung type laryngeal cough incidence, the insecure defen- sive exterior and intrinsic special type showed no statistical difference （P 〉 0.05）. And the comparative differences between the rest 2 groups are of statistical differences （P 〈 0.05）. （2） The onset time was analyzed. The results show laryngeal cough incidence from yin deficiency type and fire hyperactivity type showed no statistical difference （P 〉 0.05 ）. The rest are all of statistical difference （P 〈 0.05 ）. （3） The clinical course was analyzed. No differ- ence was found between spleen deficient phlegm type, yin deficiency and fire hyperactivity type laryngeal cough （P 〉 0.05）. Differences of the rest 2 groups showed statistical difference （P 〈 0.05）. （4） The state of illness was analyzed. The results showed statistical difference between spleen phlegm type and yin deficiency and fire hyperac- tivity type （P 〈 0.05）. No statistical difference can be found between the rest 2 groups （P 〉 0.05）. （5） The cross- tab chi-square test was carried out on the 4 groups of syndromes on the nasal allergy eye and allergy concomitant incidence. The results showed that there was no significant difference between the 4 groups （P 〉 0.05 ）. （6） On the phlegm part, the results showed difference between wind evil invading lung type and yin deficiency and fire hyper- activity type laryngeal cough （P 〉 0.05）. Differences between the rest 2 groups are of statistical significance （P 〈 0.05 ）. （7） Foreign body sensation was analyzed. The results showed no difference between insecure defensive exte- rior and intrinsi

关 键 词：喉源性咳嗽 证型 流行病学 

分 类 号：R256.11[医药卫生—中医内科学]