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出 处:《中国胸心血管外科临床杂志》2017年第10期797-802,共6页Chinese Journal of Clinical Thoracic and Cardiovascular Surgery
基 金:国家临床重点专科建设项目[2011]873
摘 要:肺气肿是以终末支气管结构异常为特征的慢性进展性疾病,终末期患者治疗方法有限。外科肺减容术是通过去除气肿化的无功能肺组织,达到改善部分肺气肿患者症状的目的,从而为肺气肿患者提供了一种有效的治疗方法。在上世纪90年代外科肺减容术被广泛认可之后,大量机构对其手术方式、围手术期死亡率、长期疗效及并发症进行了研究。其目标受益人群与手术安全性也被进一步证实。经支气管肺减容术在外科肺减容术成功开展和支气管镜技术不断发展的基础上产生,是通过支气管镜技术达到肺减容的目的。本文就外科肺减容术与经支气管镜肺减容术治疗终末期肺气肿的手术方式、安全性及疗效进行综述。Emphysema is a chronic progressive disease characterized by abnormal terminal bronchioles. Patients in end-stage have limited treatment. Lung volume reduction surgery(LVRS) is to remove the non-functional emphysematous lung tissue with the aim of palliating symptoms in selected patient with severe emphysema. It provides a new therapeutic method for emphysema. When LVRS is widely accepted after 1990s, a large number of institutions carried out the researches on surgical approaches, perioperative mortality, long-term efficacy and complications. Its targeted beneficial patients and surgical safety had been confirmed too. Bronchoscopic lung volume reduction (BLVR) successfully carried out on the basis of the development of LVRS and bronchoscopy. This article reviews the surgical approaches, safety and efficacy of LVRS and BLVR in patients with emphysema.
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