漾濞泡核桃青皮中二芳基庚烷类成分研究  

Study on diarylheptanoids from green peel of Juglans sigillata

作　　者：李冬梅 彭友伦 刘光明 

机构地区：[1]大理大学药学与化学学院,云南大理671000

出　　处：《中国中药杂志》2017年第18期3553-3556,共4页China Journal of Chinese Materia Medica

摘　　要：综合运用硅胶、Sephadex LH-20、MCI等柱色谱方法对漾濞泡核桃青皮的乙酸乙酯部位化学成分进行了研究,并利用各种波谱技术(MS,~1H-NMR,^(13)C-NMR,2D-NMR)对化合物结构进行了鉴定。结果从乙酸乙酯部位分离得到4个二芳基庚烷类化合物,分别鉴定为:二氢枫杨素(1),1-(4'-羟基苯基)-7-(3″-甲氧基苯基)-3',4″-环氧-3α-庚醇(2),枫杨素(3)和1-(4'-羟基苯基)-7-(3″-甲氧基-4″-羟基苯基)-3α-庚醇(4)。其中,化合物1(二氢枫杨素,dihydropterocarine)为新化合物,化合物2~4首次从该植物中分离得到。The chemical constituents from green peel of Juglans sigillata were isolated by column chomatographies over silica gel, Sephadex LH-20, and MCI. Four diarylheptanoids were isolated and their structures were characterized as dihydropterocarine（1）, 3＇,4″-epoxy-1-（4＇-hydroxy-phenyl）-7-（3″-methoxyl-phenyl）-heptan-3α-ol（2）, pterocarine（3）, and 1-（4＇-hydroxy-phenyl）-7-（3″-methoxy-4″-hydroxyphenyl）-heptan-3α-ol（4）. Compound 1 is a new compound, named as dihydropterocarine. Compounds 2-4 were isolated from the plant of J. sigillata for the first time.

关 键 词：泡核桃 青皮 化学成分 二芳基庚烷类 

分 类 号：R284.1[医药卫生—中药学]