丙泊酚在无痛人工流产麻醉手术中引起体动反应相关因素的研究分析  

Related factors study of propofol induced analgesia during painless induced abortion

作　　者：陈丽贞 

机构地区：[1]广东省佛山市南海经济开发区人民医院小塘院区麻醉科,广东佛山528200

出　　处：《中国医药科学》2017年第17期177-179,191,共4页China Medicine And Pharmacy

基　　金：广东省佛山市卫生和计生局医学科研立项(20170279)

摘　　要：目的探究应用丙泊酚麻醉进行无痛人工流产手术过程中导致体动反应的影响因素。方法研究对象选取为2014年1月~2016年12月之间我院行无痛人工流产手术的188例早孕妇女,均经B超检查确认为宫内妊娠,术前以2.0mg/kg剂量应用丙泊酚进行麻醉诱导,术中有体动反应时追加0.5mg/kg丙泊酚,对比发生体动反应和未发生体动反应患者的年龄、体重、孕周、分娩次数、是否贫血、是否有既往人流史、状态-特质焦虑(STAI)评分等因素差异,将单因素分析结果进一步纳入Logistic回归模型进行多因素分析,最终获得影响患者体动反应的独立相关因素。结果单因素分析结果显示,分娩次数、贫血、术前应用米索前列醇、STAI评分是影响无痛人工流产手术患者术中发生体动反应的主要因素(P<0.05);多因素分析结果显示,分娩次数、术前应用米索前列醇、STAI评分是影响无痛人工流产手术患者术中发生体动反应的独立危险因素(P<0.05)。结论分娩次数及患者的精神状态是影响丙泊酚麻醉下无痛人工流产手术患者发生体动反应的重要因素,应当针对这些情况进行干预,减少体动反应的发生。Objective To explore the influence factors of propofol anesthesia on the outcome of painless induced abortion. Methods 188 women with early pregnancy who underwent painless abortion in our hospital from January 2014 to December 2016 were selected as the study object. All the cases were confirmed as intrauterine pregnancy by B ultrasonic examination. Anesthesia was induced by propofol at 2.0mg/kg dose before operation. During the operation, 0.5mg/kg propofol was added to the body. The differences in age, weight, gestational age, number of deliveries, anemia, past history of abortion and status trait anxiety （STAI） scores were observed in patients with and without somatic reactions were compared. The single factor analysis was further incorporated into the logistics regression model for multivariate analysis. Finally, independent factors affecting the patient＇ s body motion were obtained. Results Single factor analysis showed that the number of deliveries, anemia, preoperative misoprostol and STAI score were the main factors affecting the body reaction during painless induced abortion （P 〈 0.05）. Multivariate analysis showed that the number of deliveries, preoperative misoprostol and STAI score were independent risk factors for the occurrence of somatic reactions in painless induced abortion patients （P 〈 0.05）. Conelusiort The number of deliveries and the mental status of patients are important factors that affect the response of patients undergoing painless artificial abortion under propofol anesthesia. Interventions should be directed at these conditions to reduce the occurrence of somatic reactions.

关 键 词：无痛人工流产 麻醉 丙泊酚 体动反应 

分 类 号：R614[医药卫生—麻醉学]