杞明眼保胶囊的提取工艺研究  

Study on Extracting Technology of Qimingyanbao Capsules

作　　者：苏松柏[1] 吕海涛[1] 张丽丽 黄健[1] 汤瑾[1] 朱迪 

机构地区：[1]贵阳中医学院第一附属医院,贵州贵阳550001 [2]贵州医科大学神奇民族医药学院,贵州贵阳550005

出　　处：《中国民族民间医药》2017年第18期29-31,36,共4页Chinese Journal of Ethnomedicine and Ethnopharmacy

基　　金：贵阳中医学院院内课题([2011]43号);贵州省中医药管理局课题(QZYY2012-14)

摘　　要：目的:优选杞明眼保胶囊的提取工艺。方法:以出膏率和大黄酚的含量为指标,用高效液相色谱仪测定含量,采用正交实验法优选杞明眼保胶囊的最佳提取工艺。结果:煎煮次数、煎煮时间对出膏率影响很大,其次为加水量,最佳提取工艺为加10倍量体积的水,提取3次,每次90min。结论:通过验证,优选出最佳提取工艺稳定可行。Objective To optimize the preparation process of Qimingyanbao Capsules. Methods The content of chrysophanol and chrysophanol were used as indexes, samples were analyzed by HPLC. The optimum extraction process of Qimingyanbao Capsules was determined by orthogonal experiment. Results The paste rate effect of was observed in decoction times and decoction time , the second was water addition, The results was regarded as the optimal extraction process, that is 10 times of water, 3 times of extraction and each for 90 minutes. Conclusion Experiment has been done to prove that the optimum extraction process is stable and feasible.

关 键 词：杞明眼保胶囊 提取工艺 正交实验 高效液相色谱法 

分 类 号：R284[医药卫生—中药学]