2,3-二氯苯甲醛的合成工艺研究  

Study on the Synthesis Process of 2,3-Dichlorobenzaldehyde

作　　者：姜红来 蒋校 韩勇 臧涵 申卫卫 朱成杰 

机构地区：[1]连云港市工业投资集团有限公司,江苏连云港222000

出　　处：《淮海工学院学报（自然科学版）》2017年第3期42-44,共3页Journal of Huaihai Institute of Technology:Natural Sciences Edition

摘　　要：开发出溴化氢作为水解催化剂,利用溶剂助溶实现均相水解的新型水解反应,实现了2,3-二氯苄叉二溴制备2,3-二氯苯甲醛的高效水解反应.工艺考察了溶剂、温度、溶剂用量、催化剂的质量分数及其用量对水解反应的影响,得出了最佳的水解条件:催化剂溴化氢的质量分数为9.50%时,其水溶液用量为底物质量的2.75倍,溶剂DMSO为底物质量的4倍,反应温度为140℃,水解8h.在此条件下,2,3-二氯苄叉二溴的水解转化率达99%以上.In this paper,hydrogen bromide was developed as catalyst to the hydrolysis of synthesizing 2,3-dichlorobenzaldehyde using DMSO as assisted solvent,which can supply the hydrolysis efficiently in the homogenous system.The effects of solvent,temperature,solvent content,mass fraction of catalyst and its dosage on the hydrolysis reaction were investigated and the optimum hydrolysis conditions were got.When the mass fraction of hydrogen bromide is 9.50%,the amount of aqueous solution is 2.75 times of the substrate mass,the solvent DMSO is 4times of the substrate mass,the reaction temperature is 140 ℃ and the hydrolysis is 8h.Under these conditions,the hydrolysis conversion of 2,3-dichlorobenzylidene dibromide is above 99%.

关 键 词：2 3-二氯甲苯 2 3-二氯苯甲醛 溴化氢 二甲基亚砜 

分 类 号：TQ242.1[化学工程—有机化工]