解放军第264医院165例多重耐药菌的分布及耐药性分析  

Distribution and Drug-resistance of 165 Cases of Multidrug-resistant Bacteria in the 264th Hospital of PLA

作　　者：曹瑞丽[1] 闫潇琦[1] 张德智[1] 王丽英[1] 

机构地区：[1]解放军第264医院,山西太原030001

出　　处：《中国医学创新》2017年第27期74-77,共4页Medical Innovation of China

摘　　要：目的:研究医院多重耐药菌的临床分布及对抗生素的耐药情况,指导临床合理的应用抗菌药物。方法:将2016年度检验科微生物室出具的多重耐药药敏结果,按照病原菌种类、标本来源、对抗生素的耐药情况进行统计分析。结果:本院2016年共检出165例多重耐药菌,其中革兰阴性菌占56.36%,革兰阳性菌占43.64%。居前5位的依次是表皮葡萄球菌、铜绿假单胞菌、大肠埃希菌、金黄色葡萄球菌和鲍曼不动杆菌。产ESBLs阴性菌株除对碳青霉烯类敏感之外,对其他常用抗菌药物普遍耐药。结论:规范抗生素在临床的合理应用,根据药敏结果谨慎选择抗菌药物,从源头上减少多重耐药的发生。Objective： To analyze distribution and drug-resistance of muhidrug-resistant bacteria in our hospital, and to guide clinical rational use of antibiotics.Method： The results of antibiotics-sensitivity from clinical laboratory in 2016 were analyzed according to pathogenic species, specimen source and antibiotic resistance.Result： 165 cases of muhidrug-resistant bacteria were isolated in our hospital in 2016, the Gram negative bacteria and the Gram positive bacteria accounted for 56.36% and 43.64% respectively.The top five in turn were Staphylococcus Epidermidis, Pseudomonas Aeruginosa, Escherichia Coli, Staphylococcus Aureus and Acinetobacter Bauman.ESBLs was sensitivity to Carbapenems, while resistant to other antibiotics. Conclusion ： Antibiotics should be selected according to the results of antibiotics-sensitivity, in order to promote rational application of antibiotics in clinic and reduce multiple drug resistance from the source.

关 键 词：多重耐药菌 药敏结果 抗菌药物 

分 类 号：R446.5[医药卫生—诊断学]