悬浮红细胞储存时间对妇科患者输血不良反应的影响  被引量:8

The impact of the storage duration of suspended red blood cells on blood transfusion adverse reactions in gynecological patients

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作  者:杨博[1] 李肖甫[1] 

机构地区:[1]郑州大学第三附属医院输血科,河南郑州450052

出  处:《中国输血杂志》2017年第8期917-919,共3页Chinese Journal of Blood Transfusion

摘  要:目的研究悬浮红细胞储存时间对妇科患者输血不良反应的影响。方法选取本院妇科住院输注悬浮红细胞的患者,将患者输注红细胞储存时间均≤14 d者纳入新鲜组,输注红细胞储存时间均>14 d者纳入陈旧组,分析2组患者输血后不良反应的发生率及输血后血液相关指标的差异。结果陈旧组不良反应率(2.45%),新鲜组不良反应率(1.32%),差异有统计学意义;陈旧组非溶血性发热反应率(1.42%),新鲜组非溶血性发热反应率(0.66%),差异有统计学意义;陈旧组过敏性输血反应率(1.03%),新鲜组过敏性输血反应率(0.66%),差异无统计学意义。输血后2组的电解质、血凝分析指标差异无统计学意义,陈旧组总胆红素明显高于新鲜组,差异有统计学意义。结论悬浮红细胞的储存时间对于妇科患者的输血不良反应发生有明显影响:输入储存时间长的悬浮红细胞(>14 d)使得患者更容易发生FNHTR,输入储存时间长的悬浮红细胞(>14 d)会增加患者溶血的风险并降低红细胞输注效果。Objective To study the impact of the storage duration of suspended red blood cells on blood transfusion adverse reactions in gynecological patients.Methods Gynecologic patients who received RBC transfusion therapy were divided into two groups: the fresh-group (red blood cell storage time ≤ 14 days) and the old-group (red blood cell storage time 〉 14 days). The differences in the incidence of blood transfusion adverse reactions and blood index between the two groups were analyzed.Results The incidence of blood transfusion adverse reactions of the old-group was 2.45%, the incidence of the fresh-group was 1.32%. The difference was statistically significant. The incidence of Febrile Non-hemolytic Transfusion Reactions(FNHTR) of the old-group was 1.42%, the incidence of the fresh-group was 0. 66%, the difference was statistically significant. The incidence of Anaphylactic Transfusion Reactions of the old-group was 1.03%, the incidence of the fresh- group was 0. 66%, the difference was not statistically significant. The result of the electrolyte and coagulation analysis of the two groups were not statistically significant, but the total bilirubin of the two groups were statistically significant.Conclusion The storage duration of suspended red blood cells has remarkable impact on the blood transfusion adverse reactions in gyne- cological patients: the patients of the old-group are associated with increased incidence of FNHTR compared with the fresh- group ; the patients of the old-group are associated with increased level of hemolysis and decreased effect of RBC transfusion compared with the fresh-group.

关 键 词:输血不良反应 非溶血性发热反应 过敏性输血反应 红细胞贮存损伤 

分 类 号:R457.1[医药卫生—治疗学] R331.141[医药卫生—临床医学]

 

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