重度子痫前期相关血凝指标的检测及临床意义  

Detection of Blood Coagulation Indicators in Severe Preeclampsia and Its Clinical Significance

作　　者：林容[1] 

机构地区：[1]福建医科大学省立临床医学院,福建福州350001

出　　处：《临床医学工程》2017年第10期1407-1408,共2页Clinical Medicine & Engineering

摘　　要：目的探讨重度子痫前期孕妇血凝指标的检测及临床意义。方法选取重度子痫前期孕妇47例作为观察组,正常孕妇49例作为对照组,比较两组分娩前的血凝指标、分娩结局。结果观察组的FIB、AT-Ⅲ、PLT均显著低于对照组,D-D显著高于对照组,差异均有统计学意义(P<0.05)。观察组的分娩孕周、新生儿体重、新生儿1 min阿氏评分均显著低于对照组,剖宫产率、产后出血量、新生儿NICU入住率均显著高于对照组,差异均有统计学意义(P<0.05)。结论 Fib、ATⅢ、PLT、D-D等血凝指标可作为简便的子痫前期病情变化评估的指标。Objective To explore the detection of blood coagulation indicators in pregnant women with severe preeclampsia and its clinical significance. Methods 47 cases of pregnant women with severe preeclampsia were enrolled as observation group, and 49 cases of normal pregnant women were enrolled as control group. The blood coagulation indicators before delivery, and labor outcomes were compared between the two groups. Results The levels of FIB, AT-Ⅲ and PLT of the observation group were significantly lower than those of the control group, and the D-D level was significantly higher than that of the control group （P〈0.05）. The gestational age at labor, birth weight of infants, and neonatal Apgar score at 1 min of the observation group were significantly lower than those of the control group, and the caesarean section rate, postpartum hemorrhage volume and neonatal NICU admission rate were significantly higher than those of the control group （P〈0.05）. Conclusions Fib, AT-Ⅲ, PLT and D-D can be used as simple indicators to evaluate preeclampsia changes.

关 键 词：重度子痫前期 纤维蛋白原 D-二聚体 抗凝血酶-Ⅲ 血小板计数 

分 类 号：R714.245[医药卫生—妇产科学]