137例急性发热患儿血常规及炎症因子检测结果分析  

Detection analysis of blood and inflammatory factors in 137 children with acute fever

作　　者：刘凤君[1] 韩征利[1] 刘丽丽[1] 路伟[1] 苗丽燕[1] 郑士楠 姜杉 

机构地区：[1]淄博市临淄区人民医院儿一科,山东淄博255400

出　　处：《国际检验医学杂志》2017年第18期2546-2548,共3页International Journal of Laboratory Medicine

摘　　要：目的探讨血常规及炎症因子检测结果对急性发热患儿的诊断价值。方法将137例急性发热患儿分为感染组(包括细菌性感染与非细菌性感染)和非感染组,并采集50名健康儿童(对照组)血样进行检测,比较各组患儿血常规、炎症因子检测结果。结果细菌性感染组白细胞计数(WBC)、血小板(PLT)、中性粒细胞百分比(N%)升高显著,与对照组、非感染组及非细菌性感染组比较,差异均具有统计学意义(P<0.05),而PLT及N%与非感染组比较,差异具有统计学意义(P<0.05)。细菌性感染组白细胞介素(IL)-2降低显著,与非细菌性感染组、非感染组及对照组比较,差异具有统计学意义(P<0.05);细菌性感染组IL-6、IL-10、肿瘤坏死因子(TNF-α)升高显著,与对照组、非感染组比较,差异具有统计学意义(P<0.05),IL-6与非细菌性感染组比较,差异具有统计学意义(P<0.05)。炎症因子的漏诊或误诊率最高,为18.25%,其次为血常规14.60%,而血常规+炎症因子的漏诊或误诊率最低,为8.76%。结论血常规联合炎症因子可有效降低漏诊或误诊率,对于血常规不太明确病因的患儿应联合炎症因子检测,以进一步明确病因,及早的予以治疗。Objective To investigate the diagnostic value of blood routine and inflammatory factors in children with acute fever.Methods 137 children of acute fever were divided into infection group（including bacterial infection and non bacterial infection）and non infection group.And 50 healthy children（control group）were collected.Results were compared with blood routineand inflammatory factor.Results White blood cell（WBC）,platelet（PLT）and neutrophil percentage（N%）were significantly increased in the bacterial infection group（P0.05）,and there was significant difference between the control group,the non-infection group and the non-bacterial infection group（P0.05）,and the percentage of PLT and N% was statistically significant（P0.05）compared with non-infected group.The levels of interleukin（IL）-2in the bacterial infection group were significantly lower than those in the nonbacterial infection group,the non-infection group and the control group（P0.05）.The levels of IL-6,IL-10 and TNF-αin bacterial infection group were significantly higher than those in control group and non-infected group（P0.05）.Misdiagnosis rate of inflammatory factors is the highest（18.25%）,followed by blood 14.60%,and blood combined with inflammatory factors is the lowest（8.76%）.Conclusion Blood combined with inflammatory factors can effectively reduce the misdiagnosis rate,the children with the blood unclear caused of should be combined with inflammatory factors detection in order to further clarify the cause and early treatment.

关 键 词：急性发热 炎症因子 儿童 血常规 

分 类 号：R446.1[医药卫生—诊断学] R720.597[医药卫生—临床医学]