玉米赤霉烯酮对母猪繁殖性能和胎盘免疫相关基因表达量的影响  

Effects of Zearalenone on Reproductive Performance and Placenta Immunity Related Gene Expression of Sows

作　　者：王相生[1] 孙亚宁 阮崇美[1] 张全伟[3] 张勇[1] 胡骁飞 

机构地区：[1]甘肃农业大学动物医学院,兰州730070 [2]河南省农业科学院动物免疫学重点实验室农业部动物免疫学重点实验室,郑州450002 [3]甘肃农业大学生命科学技术学院,兰州730070

出　　处：《动物营养学报》2017年第10期3696-3702,共7页CHINESE JOURNAL OF ANIMAL NUTRITION

摘　　要：本试验旨在研究饲粮中添加玉米赤霉烯酮(ZEN)对母猪繁殖性能和胎盘免疫相关基因表达量的影响。选择胎次相近、体重200 kg、妊娠第30天的长×大二元杂交母猪40头,随机分为2组,每组20个重复,每个重复1头。对照组饲喂基础饲粮,试验组饲粮在基础饲粮中添加1.5 mg/kg的ZEN。试验期74 d。结果表明,与对照组相比:1)饲粮中添加ZEN显著提高了妊娠期母猪死胎数和弱仔猪数(P<0.05),显著降低了母猪总产仔数(P<0.05);2)饲粮中添加ZEN显著提高了妊娠期母猪血清孕酮含量(P<0.05);3)饲粮中添加ZEN显著提高了妊娠期母猪胎盘中Toll样受体-2(TLR-2)和孕酮受体(PGR)基因表达量(P<0.05)。由此可见,母猪妊娠期饲粮中添加1.5 mg/kg ZEN可显著降低母猪总产仔数,并显著提高死胎数和弱仔猪数。饲粮中低水平的ZEN对母猪繁殖性能仍产生不利影响。This experiment w as to conducted to study the effects of dietary zearalenone( ZEN) on reproductive performance and placenta immunity related gene expression of sow s. Forty 30 days gestation sow s w ith similar parity and 200 kg body w eight w ere randomly divided into 2 groups w ith 20 replicates per group and 1 pig per replicate. Pigs in the control group w ere fed a basal diet,w hile others in the experimental group w ere fed the basal diet supplemented w ith 1.5 mg/kg ZEN. The experiment lasted for 74 days. The results show ed that compared w ith the control group: 1) dietary supplemented w ith ZEN significantly increased the number of stillborn piglets and number of w eak born piglets of pregnant sow s( P < 0. 05),and significantly decreased the number of total born piglets of sow s( P< 0.05); 2) dietary supplemented w ith ZEN significantly increased the serum progesterone content of pregnant sow s( P < 0. 05); 3) dietary supplemented w ith ZEN significantly increased the expressions of Toll-like receptor-2( TLR-2) and progesterone receptor( PG R) in placenta of pregnant sow s( P<0.05). In conclusion,dietary supplemented with 1.5 mg/kg ZEN can significantly decrease the number of total born piglets,and significantly increase the number of stillborn piglets and number of w eak born piglets of pregnant sow s. Dietary low level of ZEN still has adverse effect on reproductive performance of sow s.[Chinese Journal of Animal Nutrition,2017,29( 10) : 3696-3702]

关 键 词：玉米赤霉烯酮 母猪 繁殖性能 生殖激素 免疫球蛋白 基因表达 

分 类 号：S828[农业科学—畜牧学]