基于粗糙集技术的乙肝中医临床症候关联规则挖掘研究  

Research on the Assessment of Hepatitis B in TCM Based on Rough Set and Association Rules Mining

作　　者：孙继佳 王鲲 

机构地区：[1]上海中医药大学中药学院数理教研室,上海201203 [2]上海中医药大学药物临床研究中心

出　　处：《数理医药学杂志》2017年第10期1423-1425,共3页Journal of Mathematical Medicine

基　　金：上海市高校一流学科建设(A类)中药学学科创新研究基金项目(ZYX-CXYJ-014);艾滋病和病毒性肝炎等重大传染病防治项目(No.2009ZX10004-601);上海市教育委员会重点学科建设项目资助(J50301)

摘　　要：目的:采用粗糙集技术与关联规则结合的数据挖掘方法对乙肝中医临床症候规律进行研究。方法:根据所收集到的883例乙肝患者中医临床资料,采用粗糙集方法建立中医证候决策信息表,提取与乙肝证型有密切关联的症状、体征,然后利用关联规则找出不同证型下的中医临床指标的相关性。结果:通过对临床数据的挖掘分析,发现口苦、舌苔薄和脉弦等对肝胆湿热证判定以及舌胖、舌荣等对肝郁脾虚证的诊断分析具有很高的参考价值。结论:提出的方法能够有效地揭示中医临床症状之间的内在规律,对于乙肝中医临床研究工作具有一定的参考价值,并且对其他疾病的中医临床研究具有一定的参考和借鉴意义。Objective：We put forward one kind of method of data mining,which combined Rough Set and Association rules,to study the laws of Hepatitis b in Traditional Chinese Medicine clinical symptoms.Methods：On the basis of clinical data including 883 cases of Hepatitis b,we established a Rough Set decision table,extracted the key information about TCM syndromes,then with the help of Association rules algorithm,the correlations of different TCM syndromes would be found.Results：We found that the bitter taste,thin white fur of tongue and wiry pulse were important to diagnose the wetness-heat of liver and gallbladder syndrome,puffy tongue,lustrous tongue were important to diagnose liver-stagnation and spleen-deficiency syndrome.Conclusion：The application of Rough Set and would create a new perspective for not only Hepatitis b,but also for others.It may provide a useful method for the clinical research and the assessment of therapeutic effectives of TCM syndrome.

关 键 词：乙型肝炎 中医辨证 数据挖掘 粗糙集 关联规则 

分 类 号：R259[医药卫生—中西医结合]