慢性阻塞性肺疾病患者呼吸机相关性肺炎病原菌分布和临床分析  

Chronic Obstructive Pulmonary Disease Patients with Ventilator Associated Ppneumonia Pathogen Distribution and Clinical Analysis

作　　者：王海斌[1] 刘宇智[1] 金宁[1] 

机构地区：[1]广东省惠州市第六人民医院(南方医科大学附属惠阳医院)内二科,惠州516211

出　　处：《数理医药学杂志》2017年第10期1481-1483,共3页Journal of Mathematical Medicine

摘　　要：目的:分析慢性阻塞性肺疾病患者呼吸机相关性肺炎病原菌分布。方法:选取2014年4月~2016年4月在某院就诊的慢性阻塞性肺疾病患者60例,60例均进行了机械通气处理,对60例慢性阻塞性肺疾病患者的临床资料进行回顾性分析,观察呼吸机相关性肺炎病原菌的分布情况。结果:60例患者中出现呼吸机相关性肺炎病症的有38例,治愈患者有10例,好转的有18例,病死患者10例;未出现呼吸机相关性肺炎的患者有22例,死亡1例。发生呼吸机相关性肺炎的患者病死率要高于未发生呼吸机相关性肺炎的患者,两组数据差异有统计意义(P<0.05)。呼吸机相关性肺炎患者最常见的致病菌为革兰阴性杆菌,主要为铜绿假单胞菌、肺炎克雷伯菌、大肠埃希菌、鲍曼不动杆菌;革兰阳性菌主要为金黄色葡萄球菌及表皮葡萄球菌两种。结论:慢性阻塞性肺疾病患者进行机械通气后的呼吸机相关性肺炎的发生机率较高,病死率高,需要采取相对性的措施进行预防及控制,对肺炎病原菌分布情况进行观察诊断,对呼吸机相关性肺炎的预防及控制有重要意义。Objective：To analyse the chronic obstructive pulmonary disease patients with ventilator associated pneumonia pathogen distribution.Methods：60 cases of chronic obstructive pulmonary disease patients were treated in April 2014 to April 2016,and 60 cases were treated by mechanical ventilation.The clinical data of 60 patients with chronic obstructive pulmonary disease were reviewed.Then observe the distribution of ventilator-associated pneumonia pathogens.Results：There were 38 cases of ventilator-associated pneumonia in 60 patients,10 cases were cured,18 cases improved,and 10 cases died.There were 22 patients with noventilator-associated pneumonia and 1 patient died.Patients with ventilator-associated pneumonia have a higher mortality than patients without ventilator-associated pneumonia.There was significant difference between the two groups（P〈0.05）.The most common pathogens of ventilator-associated pneumonia are gramnegative bacilli,mainly Pseudomonas aeruginosa,Klebsiella pneumoniae,Escherichia coli,Acinetobacter baumannii.Gram-positive bacteria mainly includes Staphylococcus aureus and Staphylococcus epidermidis.Conclusion：The incidence of ventilator-associated pneumonia after mechanical ventilation in patients with chronic obstructive pulmonary disease is high and the mortality is high.It is necessary to take preventive measures to prevent and control the distribution of pneumonia pathogens.Machine-related pneumonia prevention and control of great significance.

关 键 词：慢性阻塞性肺疾病 呼吸机相关性肺炎 病原菌 

分 类 号：R563.9[医药卫生—呼吸系统]