寄生虫蛋白质磷酸化修饰及磷酸化蛋白质组学研究进展  

Progress on Protein Phosphorylation and Phosphoproteomics of Parasites

作　　者：赵彬[1] 唐亚兰 陆珂[2] 曹晓丹[2] 韩倩[2] 吕超[2] 王涛[2] 傅志强[2] 林矫矫[2,3] 洪炀 ZHAO Bin TANG Ya-lan LU Ke CAO Xiao-dan HAN Qian LU Chao WANG Tao FU Zhi-qiang LIN Jiao-iiao HONG Yang(J iang su Vocational College of Agriculture and Forestry, J urong , J iangsu , 212400, China Shanghai Veterinary Research Institute Chinese Academy of Agricultural Sciences, Shanghai, 200241, China Jiangsu Co-innovation Center for Prevention and Control of Important Animal Infectious Diseases and Zoonoses , Yangzhou , J iangsu , 22 5009 ,China)

机构地区：[1]江苏农林职业技术学院,江苏句容212400 [2]中国农业科学院上海兽医研究所,上海200241 [3]江苏省动物重要疫病与人兽共患病防控协同创新中心,江苏扬州225009

出　　处：《动物医学进展》2017年第10期92-97,共6页Progress In Veterinary Medicine

基　　金：国家自然科学基金青年基金项目(31402192)

摘　　要：蛋白质的磷酸化修饰是生命体内一种重要的且普遍存在的蛋白质翻译后修饰方式之一,蛋白质的磷酸化和去磷酸化是一种动态的生物调节过程,在生命过程中起着重要的作用。论文介绍了蛋白质磷酸化修饰的研究进展及其在寄生虫领域中的应用,并对其研究前景进行了展望。Protein phosphorylation is one of the most important and widespread post-translational modifications in many cellular processes. Some key regulatory functions such as phospho-signalling cascades are regulated via protein phosphorylation/dephosphorylation in a complex and dynamic manner. The research progresses of protein phosphorylation and its applications in parasitology were reviewed,and the prospect of this study was also discussed in this paper.

关 键 词：磷酸化 寄生虫 磷酸化蛋白质组学 

分 类 号：S852.7[农业科学—基础兽医学] S852.33[农业科学—兽医学]