大规模基因组重复序列识别与分类研究进展  

Research Progress on Large Scale Repeat Identification and Classification in Genomes

作　　者：葛瑞泉[1,2] 王普 李烨[1,4] 蔡云鹏 GE Ruiquan WANG Pu LI Ye CAI Yunpeng(Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, China School of Computer Science and Technology, Hangzhou Dianzi University, Hangzhou 310018, China School of Mechanical and Electronic Engineering, Jingdezhen Ceramic Institute, Jingdezhen 333403, China Key Lab for Health Informatics, Chinese Academy of Sciences, Shenzhen 518055, China Shenzhen Engineering Lab for Health Big Data Analysis, Shenzhen 518055, China)

机构地区：[1]中国科学院深圳先进技术研究院,深圳518055 [2]杭州电子科技大学计算机学院,杭州310018 [3]景德镇陶瓷大学机械电子工程学院,景德镇333403 [4]中国科学院健康信息学重点实验室,深圳518055 [5]深圳市健康大数据分析技术工程实验室,深圳518055

出　　处：《集成技术》2017年第5期55-68,共14页Journal of Integration Technology

基　　金：广东省应用型研发专项(2015B010129012);中国科学院科技服务网络项目(KFJ-SW-STS-161);杭州电子科技大学启动基金(ZX160203305002/011)

摘　　要：重复序列在基因组中普遍存在,大量实验证实其在生物进化过程中起着重要作用。目前,重复序列的发现与识别技术已经成为基因组学的研究热点,文章分类总结了有关这方面的研究进展,并对相关工具的功能特点进行了简要分析,同时对重复序列发展趋势进行了总结和展望。Repetitive sequences are prevalent in genomes. A large number of experiments have confirmed that they play an important role in biological evolution. At present, the discovery and detection of the repetitive sequences have been becoming a hot topic of genomics. This paper summarizes the research progress in this regard, and briefly analyses the associated tools. Finally, the development of repetitive sequences in future is prospected.

关 键 词：重复序列 转座子 长末端重复序列 

分 类 号：Q811.4[生物学—生物工程]