上海市部分地区健康人群流行性腮腺炎抗体水平检测  

Detection of Mumps Antibody Level in Partial Areas of Shanghai

作　　者：王刚毅[1] 胡家瑜[1] 施燕[1] 沈微娟[1] 沈荣明[1] 姜庆伍 

机构地区：[1]上海市疾病预防控制中心,上海200336 [2]复旦大学公共卫生学院,上海200032

出　　处：《中国计划免疫》2002年第4期212-213,共2页Chinese Journal of Vaccines and Immunization

摘　　要：为了解上海市部分地区健康人群流行性腮腺炎 (腮腺炎 )自然感染情况及腮腺炎IgG抗体分布情况 ,采用红血球凝集抑制试验检测腮腺炎IgG抗体。共检测了 6 91人 ,其中市区 34 2人 ,郊区 34 9人 ,年龄从 6月龄～ 2 0岁以上。结果表明 :腮腺炎IgG抗体总阳性率为 5 1 5 2 %,几何平均滴度 (GMT)为 1∶10 6 9。 6～ 8月龄婴儿抗体阳性率最低 ,为 2 85 %。市区和郊区阳性率分别为 5 6 14%、46 99%(χ2 =5 79、P <0 0 5 ) ,其差异有显著的统计学意义 ;GMT分别为 1∶14 91、1∶7 72 (t =4 76、P <0 0 1) ,其差异有极显著的统计学意义。腮腺炎自然感染率市区(5 6 14%)高于郊区 (4 6 99%)。婴儿在≥ 6月龄时应考虑接种腮腺炎疫苗。In order to recognize the status of mumps natural infection and the distribution of mumps IgG antibody in partial areas of Shanghai,we used hemagglutination inhibition test to detect the mumps IgG antibody in 691 sera,342 from urban areas and 349 from the suburbs and divided the samples into 9 age groups ranging from 6 months to over 20 years old.The results showed that the total mumps IgG antibody positive rate was 51.52%,the GMT was 1∶10.69,the lowest positive rate was seen in the age group of 6-8 months old(2.85%).The positive rates of urban and the suburbs were 56.14% and 46.99%(χ 2=5.79,P<0.01,having extremely significant difference), the GMT were 1∶14.91 and 1∶7.72(t=4.76,P<0.01,having extremely significant difference)respectively. The above data suggested that the natural infection rate of mumps in urban was higher than that in the suburbs and infants should be considered to immunize with mumps vaccine when they are over 6 months old.

关 键 词：上海 健康人群 流行性腮腺炎 IGG抗体 检测 

分 类 号：R512.1[医药卫生—内科学]