右美托咪定在神经功能性手术中的应用进展  

The research advances in the application of dexmedetomidine in nerve functional operation

作　　者：薛瑶[1] 陈锴[1] 胡彬[1] 兰忠平[1] 

机构地区：[1]延安大学附属医院麻醉科,716000

出　　处：《国际麻醉学与复苏杂志》2017年第9期833-836,共4页International Journal of Anesthesiology and Resuscitation

摘　　要：背景近年来右美托咪定（dexmedetomidine，Dex）广泛用于临床神经功能性手术。患者术前往往合并有其他一些特殊情况，如焦虑、颅内高压等，一些特殊手术患者需要术中唤醒，术后保持安全有效的镇静和镇痛。目的回顾近年来国内外诸多对Dex用于神经功能性手术围手术期的研究，对其安全有效性及具体应用进行综述。内容Dex具有镇静、镇痛的作用，且对呼吸影响轻微，改善术后认知功能，有独特的作用机制与应用。趋向深入研究Dex用于神经功能性手术的作用机制及其安全有效性，可为临床麻醉用药提供新的思路。Background Functional neurological disease often results in nerve injury. Patients with these diseases often combined with some special situation such as anxiety, intracranial high pressure. Some special surgery need intraoperative awaken. We also need keep a safe and effective sedation and analgesic in postoperative period. Dexmedetomidine（Dex） is widely used in nerve function operation in recent years. Objective This review will focus on the most recent advances regarding Dex research of neurological surgery. Content Dex has sedative and analgesic effects, with minimal influence on breathing. It can also improve postoperative cognitive function with unique mechanism. Trend The research advances of Dex on neurological surgery will contribute to develop new and safe effective anesthetics.

关 键 词：神经功能性手术 围手术期 右美托咪定 

分 类 号：R614[医药卫生—麻醉学]