胃宁散联合奥美拉唑治疗慢性浅表性胃炎的疗效观察  

Clinical observation of Weining Powder combined with omeprazole in treatment of chronic superficial gastritis

作　　者：黄春 张涛[2] 

机构地区：[1]天津市蓟州区出头岭医院消化内科,天津301943 [2]日照市人民医院内分泌科,山东日照276800

出　　处：《现代药物与临床》2017年第9期1672-1674,共3页Drugs & Clinic

摘　　要：目的观察胃宁散联合奥美拉唑治疗慢性浅表性胃炎的临床疗效。方法选取天津市蓟州区出头岭医院在2014年1月—2016年12月接诊的慢性浅表性胃炎患者128例,随机分为对照组和治疗组,每组各64例。对照组患者饭后口服奥美拉唑肠溶胶囊,40 mg/次,3次/d;治疗组在对照组的基础上口服胃宁散,1袋/次,3次/d。两组患者治疗时间均为6周。比较治疗前后两组患者临床疗效和症状评分变化。结果治疗后,对照组和治疗组的总有效率分别为85.94%、93.75%,两组比较差异具有统计学意义(P<0.05)。治疗后,两组患者出血、反酸、烧心、上腹胀痛等症状评分均显著下降,同组比较差异具有统计学意义(P<0.05);且治疗组这些评分低于对照组,两组比较差异具有统计学意义(P<0.05)。结论胃宁散联合奥美拉唑治疗慢性浅表性胃炎临床疗效显著,能有效改善患者临床症状,具有一定的临床推广应用价值。Objective To observe the clinical curative effect of Weining Powder combined with omeprazole in treatment of chronic superficial gastritis.Methods Patients （128 cases） with chronic superficial gastritis in Chutouling Hospital of Tianjin Jizhou District from January 2014 to December 2016 were randomly divided into control and treatment groups, and each group had 64 cases. Patients in the control group werepoadministered with Omeprazole Enteric-coated Capsules, 40 mg/time, three times daily. Patients in the treatment group werepo administered with Weining Powder on the basis of the control group, 1 bag/time, three times daily. Patients in two groups were treated for 6 weeks. After treatment, the change of clinical efficacy and symptom score in two groups before and after treatment was compared.Results After treatment, the clinical efficacy in the control and treatment groups were 85.94% and 93.75%, respectively, and there were differences between two groups （P 〈 0.05）. After treatment, the symptom scores of bleeding, acid regurgitation, heartburn and epigastric pain in two groups were significantly decreased, and the difference was statistically significant in the same group （P 〈 0.05）. The symptom scores in the treatment group were significantly lower than those in the control group, with significant difference between two groups （P 〈 0.05）.Conclusion Weining Powder combined with omeprazole has obvious curative effect in treatment of chronic superficial gastritis, and can significantly improve clinical symptoms, which has a certain clinical application value.

关 键 词：胃宁散 奥美拉唑肠溶胶囊 慢性浅表性胃炎 临床疗效 出血 上腹胀痛 

分 类 号：R975[医药卫生—药品]