膝关节半月板热身运动前后磁共振T_2时间变化研究  

A Research on the Changes of T_2 time by MRI for Meniscus after Warm-up Exercise

作　　者：刘彦含 张晓锦[1] 陈杰[1] 柏冬[1] Liu Yanhan Zhang Xiaojin Chen Jie Bai Dong(Department of imaging, Aerospace Medical College Hospital of Peking University, Beijing 100049, China)

机构地区：[1]北京大学航天临床医学院影像科,100049

出　　处：《医学研究杂志》2017年第9期146-150,共5页Journal of Medical Research

摘　　要：目的通过比较分析热身运动前后膝关节半月板磁共振T_2时间的变化,探讨利用T_2时间变化反映热身运动前后半月板变化的可行性。方法选择40例无膝关节相关症状的志愿者,其中男性15例,女性25例;患者年龄22~30岁,平均年龄26.32±2.1岁。在同等强度的热身运动前后对每位志愿者行右膝关节的MR T_2mapping序列成像,分别测量内、外侧半月板前角、后角、体部的T_2时间,采用配对t检验比较热身运动前后膝关节半月板T_2时间变化。结果热身运动后膝关节半月板各个部位的T_2值均增高(P=0.000);外侧半月板体部T_2值增高幅度小于内侧半月板前角(P<0.05)、内侧半月板后角(P<0.05)及外侧半月板前角(P<0.05)。结论热身运动可以增加膝关节半月板T_2时间,提示可以增加半月板内含水量,改善半月板的生理活性,对半月板起到一定的保护作用;MR T_2mapping成像技术可以评价运动前后半月板T_2时间,是评估半月板的1项可靠手段。Objective To prospectively evaluate changes in T2 relaxation times in the meniscus with warm - up excise using MRI in healthy knees, and explore the feasibility of evaluating the morphological changes of meniscus after acute warming - up by T2 time re- sponse. Methods A total of 40 healthy adult volunteers were enrolled, which included 15 males and 25 females; aged 22 - 30 years old with mean age of 26.32 ± 2.1. T2 mapping sequential imaging was performed to measure the T2 time of medial and lateral anterior, body, posterior before and after warm - up exercise. A paired Student＇s t test was used to determine the effects of warm - up exercise on T2 times. Results All volunteers showed a significant increase in T2 values after warm - up exercise in all meniscus compartments （P = 0. 000） , which may indicate changes in the biochemical composition of meniseal tissue. The lateral body compartment experienced more increment than medial anterior （ P 〈 0.05 ） , medial posterior （ P 〈 0.05 ） and lateral posterior parts （ P 〈 0.05 ） after warm - up exercise, Conclusion Longer T2 values after warm - up exercise suggest increment in the water content of knee meniscus, which may indicate im- provements in the physiological activity and protection of meniscus. T2 values in menisci have the potential to be used as biomarkers for i- dentifying meniscus changes after exercise.

关 键 词：半月板 运动 磁共振成像 T2时间 T2 MAPPING 

分 类 号：R445[医药卫生—影像医学与核医学]