胶原/生物玻璃/明胶复合材料的研究  

Study on collagen/bioglass/gelatin composite

作　　者：孟雪萍 何茜婵[1] 王芳[1] 汤克勇[1] MENG Xueping HE Xichan WANG Fang TANG Keyong(College of Materials Science and Engineering, Zhengzhou University, Zhengzhou 450001, China)

机构地区：[1]郑州大学材料科学与工程学院,河南郑州450001

出　　处：《中国皮革》2017年第10期8-12,共5页China Leather

基　　金：国家自然科学基金(51373158;51673177);河南省科技创新杰出人才(124300510030)资助项目

摘　　要：将胶原、生物玻璃和明胶按照不同的比例复合制备了一种新型复合材料,通过X射线衍射(XRD)和扫描电子显微镜(SEM)表征了生物玻璃和复合材料的结构与形貌,并研究了其机械性能和孔隙率。结果表明:复合材料的机械强度基本达到松质骨的强度需要,具有较高的孔隙率,达50%以上。该新型复合材料有望用于骨组织工程中的骨替代材料。The advanced composite material was prepared with collagen, bioglass and gelatin compounded in different proportions. The structure and morphology of bi by X-ray diffraction （XRD） and scanning electron oglass and collagen/bioglass/gelatin composite were investigated microscope （SEM）. Mechanical properties and porosity of the composite were tested as well. The results indicate that the compressive strength meets the requirement of spongy bone. Porosity study shows that the biomaterial is highly porous, above 50%. It can be expected for the application of bone substitute material in bone tissue engineering.

关 键 词：胶原 明胶 生物玻璃 支架材料 骨组织工程 

分 类 号：R318.08[医药卫生—生物医学工程] TB332[医药卫生—基础医学]