Preparation and Biocompatibility of Polyester Films Grafted with Functional mPEG Copolymers  

作　　者：MA Yanhong JIANG Yan LIANG Yuan ZHANG Weiwei ZHANG Hongwen ZHANG Rong 

机构地区：[1]Institute of Agro-product Processing, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, P. R. China [2]College of Materials Science and Engineering, Changzhou University, Changzhou 213164, P. R. China [3]College of Life Science, Agriculture and Forestry, Qiqihar University, Qiqihar 161006, R R. China [4]Jiangsu Chenguang Paint Co., Ltd., Changzhou 213154, P. R. China

出　　处：《Chemical Research in Chinese Universities》2017年第5期847-852,共6页高等学校化学研究（英文版）

基　　金：Supported by the National Natural Science Foundation of China（No.51203015）, the Natural Science Foundation of Jiangsu Province, China~o.BK2012786）, Qing Lan Project and the Changzhou Science and Technology Support Program, China （No.CE20150002）.

摘　　要：The surface ofpoly（ethylene terephthalate）（PET） films is inert, hydrophobic, and incompatible with blood, which has limited its practical bioapplication. In this case, better biocompatibility could be achieved by surface modification. In this study, the grafted copolymer of functional methoxypolyethylene glycol（mPEG） derivatives and styrene from the PET surfaces was prepared via surface-initiated atom transfer radical polymerization（SI-ATRP）. The structures, composition, properties and surface morphology of the grafted PET films were characterized by Fourier transform infrared spectroscopy（FTIR）, X-ray photoelectron spectroscopy（XPS）, contact angle measurements and scanning electronic microscopy（SEM）. The results indicate that the surface of the PET films has been covered by a thick targeted copolymer layer that converted the hydrophobic surface of PET to an amphiphilic surface. The bacte- rial adhesion and cell culture results indicate the copolymer-grafted PET film may possess good biocompatibility.The surface ofpoly（ethylene terephthalate）（PET） films is inert, hydrophobic, and incompatible with blood, which has limited its practical bioapplication. In this case, better biocompatibility could be achieved by surface modification. In this study, the grafted copolymer of functional methoxypolyethylene glycol（mPEG） derivatives and styrene from the PET surfaces was prepared via surface-initiated atom transfer radical polymerization（SI-ATRP）. The structures, composition, properties and surface morphology of the grafted PET films were characterized by Fourier transform infrared spectroscopy（FTIR）, X-ray photoelectron spectroscopy（XPS）, contact angle measurements and scanning electronic microscopy（SEM）. The results indicate that the surface of the PET films has been covered by a thick targeted copolymer layer that converted the hydrophobic surface of PET to an amphiphilic surface. The bacte- rial adhesion and cell culture results indicate the copolymer-grafted PET film may possess good biocompatibility.

关 键 词：Poly（ethylene terephthalate） film Surface-initiated atom transfer radical polymerization（SI-ATRP） Bio- compatibility 

分 类 号：O631.5[理学—高分子化学] TS727.2[理学—化学]