生物可吸收支架研究进展  

Research Progress of Bioresorbable Scaffold

作　　者：刘青 崔淑君 赵庆洪 陈明[2] 郑博[2] 霍勇[2] LIU Qing CUI Shujun ZHAO Qinghong CHEN Ming ZHENG Bo HUO Yong(Beijing Advanced Medical Technologies Co. Ltd., Beijing, 100085 Peking University First Hospital, Beijing, 100034)

机构地区：[1]北京阿迈特医疗器械有限公司,北京市100085 [2]北京大学第一医院,北京市100034

出　　处：《中国医疗器械杂志》2017年第5期357-361,共5页Chinese Journal of Medical Instrumentation

摘　　要：生物可吸收支架(Bioresorbable Scaffold,BRS)代表一种新的冠状动脉介入治疗方法。BRS通过提供暂时性的支撑,保障了治疗早期的血管通畅和急性获益,完成"使命"后,逐渐被吸收消失,将病变血管解放出来,使血管正性重构和晚期管腔扩大成为可能,特别是在分叉病变中,分支血管最终能够实现无支架干扰。这种独特的性能是传统的永久性金属支架实现不了的,因而BRS自出现以来引起了广泛的关注。该文介绍了BRS的研究背景、研究现状,并对BRS面临的挑战及该领域的发展方向做了展望。Bioresorbable scaffold （BRS） represents a new technique for percutaneous coronary intervention （PCI）. Through providing temporary support to the vessel, it guarantees patency and acute benefits of the vessel in the early treatment stage. When completing its ＂mission＂, BRS gradually disappears by resorption. So it allows late vessel positive remodeling without ＂metal cage＂ effect and leaves only healed natural vessel after the full absorption, especially in the bifurcation lesion, the branch of the vessels can eventually achieve stent-free interference. This unique performance can not be achieved by the traditional permanent metal stent, so BRS has attracted more and more attention since its appearance. This article reviewed the research background, current status and challenges of BRS, then discussed its future development trends.

关 键 词：生物可吸收支架 血管内皮细胞 经皮冠脉介入治疗 血管支架 

分 类 号：R541.4[医药卫生—心血管疾病] R318.08[医药卫生—内科学]