阴、阳离子型水溶性卟啉的有效合成  

Efficient Synthesis of Anionic and Cationic Water-Soluble Porphyrins

作　　者：常毅 刘梦阳 牛梦园 Chang Yi Liu Mengyang Niu Mengyuan(School of Chemistry and Chemical Engineering, Henan Normal University, Xinxiang 45300)

机构地区：[1]河南师范大学化学化工学院,新乡453007

出　　处：《有机化学》2017年第9期2442-2448,共7页Chinese Journal of Organic Chemistry

基　　金：河南省高等学校重点科研项目计划(No.16A150012);河南师范大学青年科学基金(No.214QK15);河南师范大学博士科研启动基金(No.qd15113)资助项目~~

摘　　要：以meso-四(4-吡啶基)卟啉和meso-四(4-羟基苯基)卟啉为原料,三乙二醇单甲醚单元取代和锰离子配位作为功能性修饰手段,按照优化的反应条件,高效合成了吡啶基阳离子型和磺酸基阴离子型水溶性卟啉化合物.该类方法操作简单、收率高、反应条件温和,为同类型水溶性卟啉的合成提供了很好的合成方法.A kind of cationic water-soluble porphyrin containing pyridinium group and a kind of anionic water-soluble porphyrin containing sulfonic group were synthesized efficiently according to the chosen conditions. During the synthesis process, 5,10,15,20-tetra（pyridin-4-yl）porphyrin and 5,10,15,20-tetra-phenol porphyrin were chosen as the precursors, while triethylene glycol monomethyl ether and manganese were introduced on porphyrin as the functional group. These procedures have the advantages of operation simplicity, high yields, mild conditions, and provide a good method for the synthesis of similar types of water soluble porphyrins at the same time.

关 键 词：水溶性 卟啉 锰卟啉 取代基团 合成 修饰 

分 类 号：O621.3[理学—有机化学]