2015年晴隆县8月龄～24岁健康人群脊髓灰质炎、流行性脑脊髓膜炎、流行性乙型脑炎抗体水平调查  

Serum levels of antibodies against poliomyelitis,epidemic cerebrospinal meningitis and epidemic encephalitis B among healthy population aged between 8 months and 24 years in Qinglong County,2015

作　　者：郑云[1] 孙启刚[1] 袁勇[1] 蒋万权 

机构地区：[1]贵州省晴隆县疾病预防控制中心,贵州晴隆561400

出　　处：《实用预防医学》2017年第11期1357-1360,共4页Practical Preventive Medicine

摘　　要：目的了解2015年晴隆县8月龄~24岁健康人群脊髓灰质炎、流行性脑脊髓膜炎、流行性乙型脑炎3种传染病特异性Ig G抗体水平,为相应传染病预防和控制提供科学依据。方法 2015年3-4月,以乡镇为单位,每个乡镇随机抽取一个行政村为调查点,每个调查点将8月龄~24岁健康人群分成8个年龄组,每个年龄组抽取30人共3 360人静脉血分离血清,采用酶联免疫吸附法(ELISA)检测3种传染病病源特异性Ig G抗体水平,分析抗体水平差异性。结果 2015年晴隆县8月龄~24岁健康人群脊髓灰质炎、流行性脑脊髓膜炎和流行性乙型脑炎Ig G抗体水平阳性率分别为75.51%、43.87%和31.64%。不同年龄、地区调查人群三项抗体阳性率差异有统计学意义(P<0.05),脊髓灰质炎抗体最高,流行性乙型脑炎最低。不同性别调查人群脊髓灰质炎抗体阳性率差异有统计学意义(P<0.05),女性高,男性低;流行性脑脊髓膜炎和流行性乙型脑炎Ig G抗体阳性率差异无统计学意义。结论 2015年晴隆县8月龄~24岁健康人群脊髓灰质炎、流行性脑脊髓膜炎、流行性乙型脑炎3种特异性Ig G抗体水平均不高,未达到卫生和计划生育委员会规定的85%基本水平,必须采取有效工作措施,提高儿童基础免疫全程接种率。Objective To investigate the specific IgG antibody levels of 3 kinds of infectious diseases, including poliomyelitis, epidemic cerebrospinal meningitis and epidemic encephalitis B among healthy population aged between 8 months and 24 years in Qinglong County in 2015 so as to provide a scientific basis for prevention and control of the above-mentioned infectious diseases. Methods Taking the township as a unit, an administrative village was randomly selected from each town to serve as the sur- veyed spot from March to April in 2015. The healthy people aged between 8 months and 24 years in each surveyed spot were divid- ed into 8 age groups and 30 people were selected from each age group. Venous blood samples of total 3,360 people were abstract- ed to separate serum, and enzyme-linked immunosorbent assay （ ELISA） was used to detect the specific IgG antibody levels of 3 kinds of infectious diseases. The differences in the levels of 3 kinds of specific IgG antibodies were analyzed. Results The posi- tive rates of IgG antibodies against poliomyelitis, epidemic eerebrospinal meningitis and epidemic encephalitis B in the healthy pop- ulation aged between 8 months and 24 years in Qinglong County in 2015 were 75.51%, 43.87% and 31.64% respectively. There were statistically significant differences in the positive rates of the 3 kinds of antibodies among people with different ages and re- gions （ all P〈0.05）. The level of IgG antibody against poliomyelitis was the highest, while that of IgG antibody against epidemic encephalitis B was the lowest. The positive rate of IgG antibody against poliomyelitis was higher in the females than in the males, with a statistically significant difference （ P〈0.05 ）. No statistically significant differences were found in the positive rates of IgG an- tibodies against epidemic cerebrospinal meningitis and epidemic encephalitis B. Conclusions The levels of specific IgG anti- bodies against poliomyelitis, epidemic cerebrospinal meningitis and epidemic encephalitis B in the hea

关 键 词：脊髓灰质炎 流行性脑脊髓膜炎 流行性乙型脑炎 健康人群 抗体水平阳性率 

分 类 号：R512.4[医药卫生—内科学]