中西药治疗2型糖尿病合并稳定性心绞痛的临床研究  

The effect of Pioglitazone combined with liraglutide in type 2 diabetes mellitus with OSAHS and on the levels of adiponectin

作　　者：刘颖[1] 张军[1] 王军媛[1] 赵建红[1] 王明星 刘晓曼[1] LIU Ying ZHANG Jun WANG Jun-yuan ZHAO Jian-hong WANG Ming-xing LIU Xiao-man(Tangshan Traditional Chinese Medicine Hospital, Hebei Tangshan 063000, Chin)

机构地区：[1]唐山市中医医院内分泌科,河北唐山063000

出　　处：《临床医药文献电子杂志》2017年第50期9703-9704,9706,共3页Electronic Journal of Clinical Medical Literature

摘　　要：目的观察我院自拟益气养阴方加味对2型糖尿病合并稳定性心绞痛的疗效,探索2型糖尿病合并稳定性心绞痛的中医证型规律。方法将92例患者按随机数字表法分为3组:西药组(26例)经常规西药治疗。中药组(29例)经常规西药联合中药益气养阴方治疗。中药辩证组(37例)经常规西药联合我院自拟益气养阴方治疗,并经辩证加用理气、活血、祛痰中药。结果治疗后,三组血脂指标均较治疗前明显改善,P<0.05,中药组TC、TG、LDL-C指标水平均低于西药组各指标水平,HDL-C水平高于西药组,P<0.05,中药辩证组TC、TG、LDL-C指标水平均低于中药组,HDL-C水平高于中药组P<0.05。中药组心绞痛疗效总有效率高于西药组,P<0.05;中药辩证组心绞痛疗效总有效率高于中药组,P<0.05。中药组不良心血管事件发生率低于西药组,P<0.05;中药辩证组不良心血管事件发生率低于中药组,P<0.05。结论以益气养阴法为治疗大法同时进行中医药辩证论治能够有效治疗2型糖尿病伴稳定性心绞痛,可有降低血脂水平,提高心绞痛疗效,降低不良心血管事件发生率。Objective To observe the curative effect of Jiawei Shengmai Decoction on type 2 diabetic patients with stable angina pectoris,TCM syndrome type and explore the law of type 2 diabetic patients with stable angina. Methods 92 patients according to the random number table method, were randomly divided into 3 groups： 26 cases in the western medicine group, were accepted with Western medicine routine treatment.Chinese medicine group of 29 cases, were accepted with Western medicine routine treatment combining with traditional Chinese medicine of shengmaiyin. Chinese medicine dialectical group of 37 cases,were accepted with additional different Traditional Chinese Medicine according to differentiation of symptoms and signs of qi stagnation group, blood stasis group, phlegm and Qi,on the basis of Western medicine routine treatment combining with traditional Chinese medicine. Results After treatment, three groups with blood lipid indexes were significantly improved compared with before treatment, P〈0.05, Chinese medicine group TC, TG,LDL-C index was lower than the level of each index HDL-C was higher than the western medicine group, western medicine group,P〈0.05,tmditional Chinese medicine group TC, TG,LDL-C index were significantly lower than that of the traditional Chinese medicine group, the level of HDL-C was higher than the Chinese medicine group P〈0.05.traditional Chinese medicine group of angina pectoris total effective rate higher than the western medicine group,P〈0.05;traditional Chinese medicine group of angina pectoris total efficiency was higher than that of the traditional Chinese medicine group the incidence of adverse cardiovascular events in P〈0.05. Chinese medicine group was lower than that in western medicine group, P〈0.05; the incidence of adverse cardiovascular events in TCM dialectical group was lower than that of traditional Chinese medicine group,P〈0.05. Conclusion By supplementing qi and nourishing yin for treatment and traditional Chinese medicine dialectical treatment can be effect

关 键 词：2型糖尿病 稳定性心绞痛 益气养阴法 中药辩证 

分 类 号：R587.2[医药卫生—内分泌]