左旋布比卡因腰-硬联合麻醉在儿童阑尾炎切除中的麻醉效果及安全性研究  

The efficacy and safety of levobupivacaine combined with epidural anesthesia in appendectomy in children

作　　者：郑德全 ZHENG De Quan(Linyi women and children＇s hospital,Shandong Linyi 276000,Chin)

机构地区：[1]临沂妇女儿童医院,山东临沂276000

出　　处：《临床医药文献电子杂志》2017年第47期9252-9253,共2页Electronic Journal of Clinical Medical Literature

摘　　要：目的综合分析左旋布比卡因腰-硬联合麻醉在儿童阑尾炎切除中的麻醉效果及安全性。方法选取2016年1月~2017年1月我院收治的阑尾炎患儿120例作为研究对象,根据麻醉方法分为左旋布比卡因腰-硬联合麻醉组与硬膜外麻醉组,各60例。分析左旋布比卡因腰-硬联合麻醉组与硬膜外麻醉组患儿的临床麻醉优良率、麻醉起效时间、局部麻醉药物用量、不同时间点(术后1 h、5 h、10 h)视觉疼痛评分比较、以及麻醉前后心率变化等参数指标。结果 (1)左旋布比卡因腰-硬联合麻醉组优良率显著高于硬膜外麻醉组(P<0.05);(2)左旋布比卡因腰-硬联合麻醉组麻醉起效时间显著短于硬膜外麻醉组(P<0.05);(3)麻醉前,两组患者心率比较,差异无统计学意义(P>0.05);麻醉后(牵拉阑尾时),两组患者心率比较,差异有统计学意义(P<0.05);(4)左旋布比卡因腰-硬联合麻醉组局部麻醉药物用量显著少于硬膜外麻醉组(P<0.05);(5)左旋布比卡因腰-硬联合麻醉组视觉疼痛评分术后1 h、5 h、10 h显著低于硬膜外麻醉组(P<0.05)。结论左旋布比卡因腰-硬联合麻醉在儿童阑尾炎切除中的麻醉效果显著。Objective To evaluate the efficacy and safety of levobupivacaine combined with epidural anesthesia in appendectomy in children.Methods From January 2016 to January 2017 in our hospital 120 cases of appendicitis in children as the research object, according to the method of anesthesia is divided into levobupivacaine for combined spinal epidural anesthesia group and epidural anesthesia group, each of 60 cases. The excellent rate of clinical anesthesia levobupivacaine for combined spinal epidural anesthesia group and epidural anesthesia group of patients, the onset time of anesthesia local anesthesia, drug dosage, different time points （after 1 h, 5 h, 10 h） compared with the visual analogue scale, and the change of heart rate before and after anesthesia and other parameters.Results The combined spinal epidural anesthesia with levobupivacaine group fine rate was significantly higher than that of the epidural anesthesia group （P〈 0.05）; the combined spinal epidural anesthesia with levobupivacaine anesthesia onset time was significantly shorter than the epidural anesthesia group （P〈 0.05）; 3 before anesthesia, compared two groups of patients with heart rate, the difference was not statistically significant （P〉O.05） after anesthesia; （pull the appendix）, compared two groups of patients with heart rate, the difference was statistically significant （P〈0.05）; the combined spinal epidural anesthesia with levobupivacaine group of local anesthetic drug dosage was less than epidural anesthesia group （P〈0.05）; the cloth left bupivacaine combined spinal epidural anesthesia The visual pain scores in the drtmken group were significantly lower than those in the epidural anaesthesia group （1 h, 5 h, 10 h） after surgery （P〈0.05）.Conclusion The anesthesia effect of lumbar bupivacaine combined with lumbar - hard anesthesia in children with appendicitis is significant.

关 键 词：左旋布比卡因 腰-硬联合麻醉 儿童阑尾炎切除 麻醉效果 

分 类 号：R614[医药卫生—麻醉学]