参茸五子丸质量标准的建立  

Establishment of Quality Standard for Shenrong Wuzi Pill

作　　者：焦玉[1] 黄德红[1] 王兵娥[1] 万宏[1] 崔瑾瑾[1] 胡思荣[1] 

机构地区：[1]湖北中医药大学附属襄阳医院药学部,湖北襄阳441000

出　　处：《湖北医药学院学报》2017年第4期300-303,F0003,共5页Journal of Hubei University of Medicine

摘　　要：目的:建立参茸五子丸的质量标准。方法:根据处方药物组成,采用薄层色谱法对制剂中的枸杞子、黄柏进行鉴别,高效液相色谱法测定制剂中橙皮苷的含量。结果:定性鉴别方法准确、专属性强。橙皮苷进样浓度在6.67~66.71μg·m L范围内与其峰面积呈良好线性关系,平均回收率为98.87%,RSD为1.11%(n=6)。结论:建立的质量控制方法准确、快速、重现性好,能有效控制该制剂的质量。Objective To establish the quality method of Shenrong wuzi pill. Methods According to the prescription,fructus lycii and phellodendron chinense were identified by TLC method,and hesperidin was determined by HPLC. Results The identification method was accurate and specific. Injection concentration with the range from 6.67 to 66.71 μg·m L-1of hesperidin was good. The average recovery rate was 98.87%,and RSD was 1.11%（ n = 6）. Conclusion The established method was accurate,quickly,and reproducibility was good. It could be effectively used in quality control.

关 键 词：参茸五子丸 薄层鉴别 含量测定 枸杞子 黄柏 橙皮苷 

分 类 号：R286.0[医药卫生—中药学]